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Metarrestin, also known as NCATS-SM0590, is a specific inhibitor of perinuclear compartment (PNC).
Z-VAD(OH)-FMK, also known as Z-Val-Ala-Asp-(OH)-Fluoromethyl Ketone, is an irreversible tripeptide inhibitor of all...
Nirmatrelvir, also known as PF-07321332 (brand name: Paxlovid), is an orally bioavailable 3C-like protease (3CLPRO)...
SJ6986 is a Potent, Selective, and Orally Bioavailable Small-Molecule GSPT1/2 Degrader from a Focused Library of...
ALC-0159 is a PEG/lipid conjugate (i.e. PEGylated lipid), specifically, it is the N,N-dimyristylamide of...
ALC-0315 is a synthetic cationic lipid (or ionizable lipid). It is a colorless oily material, It has attracted...
CAS#: 2561414-57-9 (HCl)
GNF2133 is a potent and selective DYRK1A inhibitor (IC50 = 6 nM). In vitro, GNF2133 is able to proliferate both...
MKC-1 is an orally bioavailable, small-molecule, bisindolylmaleimide cell cycle inhibitor with potential...
Dapaconazole is an antifungal drug candidate. Phase II trials showed that Dapaconazole tosylate is non-inferior to...
HQ461 is a Molecular-glue degrader. HQ461 acts by promoting an interaction between CDK12 and DDB1-CUL4-RBX1 E3...
VUN73874, also known as GOT1 inhibitor 2c, is a glutamate-oxaloacetate transaminase 1 (GOT1) inhibitor. This...
CUN43389, also known as SMS1-IN-1 and SAPA1j, is a SAPA inhibitor (sphingomyelin synthase 1 inhibitor). SAPA 1j was...
Lateritin is An Acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor and a platelet aggregation inhibitor isolated...
PHPS1 is an inhibitor of the protein tyrosine phosphatase Shp2. PHPS1 also efficiently inhibits activation of Erk1/2...
iGOT1-01 is an inhibitor of aspartate aminotransferase 1 (glutamate oxaloacetate transaminase 1, GOT1).
BAY-179 is a potent, selective, and species cross-reactive OXPHOS complex I inhibitor.
VV116, also known as JT001, is an oral drug candidate of nucleoside analog against SARS-CoV-2. VV116 is a deuterated,...
SM-102 is an ionizable amino lipid that has been used in combination with other lipids in the formation of lipid...
CAS#: 450839-40-4 (free base)
ABT-100 is an orally bioavailable farnesyltransferase inhibitor. ABT-100 inhibited proliferation of cells in vitro...
Ro 08-2750 is a potent and selective Nerve growth factor (NGF) inhibitor that binds the NGF dimer (KD ~ 1 μM). NGF...
Sirolimus, also known as rapamycin, is a natural macrocyclic lactone produced by the bacterium Streptomyces...
LQZ-7I is a malarial protease PfSUB1 inhibitor. LQZ-7I showed significantly improved activity and is the focus of...
Fluzoparib, also known as SHR3162, is a poly (ADP-ribose) polymerase inhibitor (PARP) inhibitor potentially for the...
CAS#: 2252316-16-6 (free base)
TBAJ-587 is a potent anti-tuberculosis agent. TBAJ-587 inhibits M.tb strain H37Rv growth with MIC90s of 0.006 and...
NVP-RXI570, also known as CUN79177 and BRM/BRG1 ATP Inhibitor-1, is an orally Active Inhibitors (IC50=5 nM) of...