Newest Products

PF-431396

CAT#: 407200
CAS#: 717906-29-1

PF-431396 is a potent and selective focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2) inhibitor...

PYR-41

CAT#: 406481
CAS#: 418805-02-4

PYR-41 is a ubiquitin-activating enzyme inhibitor (UBE1 inhibitor). PYR-41 blocks ubiquitination reactions but...

XL177A

CAT#: 408090
CAS#: 2417089-74-6 (S-isomer)

XL177A is a potent USP7 inhibitor. XL177A irreversibly inhibits USP7 with sub-nM potency and selectivity across the...

RG7800

CAT#: 526734
CAS#: 1449598-06-4

RG7800, also known as RO6885247 is a potent and selective SMN2 splicing modifier, which is currently under human...

GGTI-298 TFA

CAT#: 206802
CAS#: 1217457-86-7 (TFA)

GGTI-298 is a potent geranylgeranyltransferase-I (GGTase-I) inhibitor with potential antitumor actrivity. GGTI-298...

GDC-0941 (Pictilisib)

CAT#: 201395
CAS#: 957054-30-7 (free base)

Pictilisib, also known as Pictrelisib, GDC-0941, RG7321 and GNE0941 , is an orally bioavailable, and is a potent...

Galeterone

CAT#: 205646
CAS#: 851983-85-2

Galeterone, also known as TOK-001 and NX41765; is an orally bioavailable small-molecule androgen receptor modulator...

BAZ2-ICR

CAT#: 406642
CAS#: 1665195-94-7

BAZ2-ICR is an excellent chemical probe for functional studies of the BAZ2 bromodomains in vitro and in vivo. The...

SAG (Smo agonist) free base

CAT#: 407108
CAS#: 912545-86-9 (free base)

SAG is a potent Smoothened (Smo) receptor agonist (Kd = 59 nM); sag antagonizes cyclopamine action at the Smo...

Nolatrexed HCl

CAT#: 206596
CAS#: 152946-68-4 (HCl salt)

Nolatrexed, also known as AG337, is a thymidylate synthase inhibitor with potential anticancer activity. A phase II...

Retapamulin

CAT#: 300270
CAS#: 224452-66-8

Retapamulin, also known as SB-275833, is a newer topical agent of pleuromutilin class approved by the Food and Drug...

Flutamide

CAT#: 100374
CAS#: 13311-84-7

Flutamide, also known as SCH13521, is a toluidine derivative and nonsteroidal antiandrogen that is structurally...

IKK-16 (free base)

CAT#: 407163
CAS#: 873225-46-8 (free base)

IKK-16 is a potent and slective inhibitor of IκB kinase (IKK) (IC50 values are 40, 70 and 200 nM for IKKβ, IKK...

Pritelivir mesylate

CAT#: 330140
CAS#: 1428333-96-3 (mseylate)

Pritelivir, also known as AIC-316 and BAY 57-1293, is a potent helicase primase inhibitor. BAY 57-1293 inhibits...

SAN50900

CAT#: 555980
CAS#: 2229050-90-0

SAN50900, also known as FLT3-IN-3, is a potent and selective FLT3 inhibitor. SAN50900 displays nanomolar activity in...

Elimusertib free base

CAT#: 333061
CAS#: 1876467-74-1 (free base)

Elimusertib, also known as BAY-1895344, is a potent and selective ATM inhibitor. BAY 1895344 shows potent anti-tumor...

Wnt-C59

CAT#: 406605
CAS#: 1243243-89-1

Wnt-C59 is a potent porcupine (PORCN) inhibitor. Wnt-C59 inhibits PORCN activity in vitro at nanomolar...

Conoidin A

CAT#: 555967
CAS#: 18080-67-6

Conoidin A inactivates peroxiredoxins by covalently binding to the catalytic cysteine on the enzyme.

Pizuglanstat

CAT#: 584814
CAS#: 1244967-98-3

Pizuglanstat is a hematopoietic prostaglandin synthase inhibitor.

Aloxistatin (E-64d)

CAT#: 319511
CAS#: 88321-09-9

Aloxistatin (E-64d), is a selective cysteine protease inhibitor or calpain and autophagy inhibitor. E-64d prevents...

CX-6258

CAT#: 406247
CAS#: 1202916-90-2 (free base)

CX-6258 is a pan-Pim kinases inhibitor with excellent biochemical potency and kinase selectivity. CX-6258 exhibited...

C-176 STING inhibitor

CAT#: 555342
CAS#: 314054-00-7

C-176 (C-176) is a covalent, in vivo-active, small-molecule inhibitor of STING, attenuates STING-associated...

N-Acetyl calicheamicin

CAT#: 408158
CAS#: 108212-76-6

N-Acetyl calicheamicin is a derivative of calicheamicin, and is a potent enediyne antitumor antibiotic....

Azoramide

CAT#: 329524
CAS#: 932986-18-0

Azoramide is a small-molecule modulator of the unfolded protein response with antidiabetic activity. Azoramide...

COH29

CAT#: 206562
CAS#: 1190932-38-7

COH29 is an orally available, aromatically substituted thiazole and inhibitor of the human ribonucleotide reductase...