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CAS#: 193000-39-4 (HCl)
ZM323881 is a potent and selective inhibitor of VEGF-R2 tyrosine kinase in vitro (IC(50) < 2 nM), compared with other...
Chromeceptin is an IGF2 inhibitor. Chromeceptin inhibits Insulin-like growth factor 2 (IGF2) signaling by a process...
THS-044 binding stabilizes the HIF2α PAS-B folded state, for regulating HIF2 activity in endogenous and clinical...
BMS-905 is a Dual Antagonist of Toll-like Receptors 7 and 8 (TLR7/8)
Mebeverine acid is a metabolite of the antispasmodic agent mebeverine.
CAIX Inhibitor S4
CAIX Inhibitor S4 is an inhibitor of carbonic anhydrase IX. It is selective for CAIX over CAI and CAII but does...
CAS#: 111755-76-1 (bromide)
Propargylcholine bromide is an alkynyl derivative of choline that has a propargyl group in place of one methyl group....
JNJ-10198409, also known as RWJ-540973, is an inhibitor of PDGF-BB tyrosine kinase with an IC50 value of 4.2 nM....
ML-SI3 is a chemical compound which acts as an "antagonist" (i.e. channel blocker) of the TRPML family of calcium...
Bimiralisib free base
CAS#: 1225037-39-7 (free base)
Bimiralisib, also known as PQR309, is an orally bioavailable pan inhibitor of phosphoinositide-3-kinases (PI3K) and...
Mavorixafor free base
CAS#: 558447-26-0 (free base)
Mavorixafor, also known as AMD11070, AMD070, X4P-001, is an orally bioavailable and potent CXCR4 inhibitor. AMD11070...
CAS#: 2561414-57-9 (HCl)
GNF2133 is a potent and selective DYRK1A inhibitor (IC50 = 6 nM). In vitro, GNF2133 is able to proliferate both...
Sirolimus, also known as rapamycin, is a natural macrocyclic lactone produced by the bacterium Streptomyces...
ALC-0315 is a synthetic cationic lipid (or ionizable lipid). It is a colorless oily material, It has attracted...
PFK-158, also known as ACT-PFK-158, is an inhibitor of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatases...
CAS#: 108392-02-5 (sodium)
DOPA lipid, also known as 18:1 PA; 1,2-dioleoyl-sn-glycero-3-phosphate (sodium salt); PA(18:1(9Z)/18:1(9Z)); is a...
CAS#: 877387-37-6 (free base)
GSK5182 is a specific inverse agonist for estrogen-related receptor γ.
Epiblastin A is a Casein Kinase 1 (CK1) inhibitor. Epiblastin A engages CK1 isoenzymes in cell lysate and induces...
CAS#: 848133-17-5 (free base)
HKI-357 is an irreversible dual inhibitor of EGFR and ERBB2. HKI-357 suppresses EGFR autophosphorylation (at Y1068),...
MKC3946 is a potent and soluble IRE1α inhibitor. MKC-3946 blocks XBP1 mRNA splicing and exhibits cytotoxicity against...
NAI-N3 is a probe for icSHAPE (in vivo click selective 2'-hydroxyl acylation and profiling experiment). It acylates...
SM-102 is an ionizable amino lipid that has been used in combination with other lipids in the formation of lipid...
ALW-II-41-27 is a Eph receptor tyrosine kinase inhibitor. pharmacologic inhibition of EPHA2 by the small-molecule...
NVS-PAK1-1 is a specific allosteric PAK1 inhibitor.
SKI-178 is a sphingosine kinase 1 (SphK1) inhibitor (IC50 = 0.1-1.8 μM). SKI-178 induces prolonged mitosis followed...