Newest Products

ZM323881 HCl

CAT#: 405610
CAS#: 193000-39-4 (HCl)

ZM323881 is a potent and selective inhibitor of VEGF-R2 tyrosine kinase in vitro (IC(50) < 2 nM), compared with other...

Chromeceptin

CAT#: 556121
CAS#: 331859-86-0

Chromeceptin is an IGF2 inhibitor. Chromeceptin inhibits Insulin-like growth factor 2 (IGF2) signaling by a process...

THS-044

CAT#: 462444
CAS#: 62054-67-5

THS-044 binding stabilizes the HIF2α PAS-B folded state, for regulating HIF2 activity in endogenous and clinical...

BMS-905

CAT#: 556120
CAS#: 2205846-49-5

BMS-905 is a Dual Antagonist of Toll-like Receptors 7 and 8 (TLR7/8)

Mebeverine Acid

CAT#: 556119
CAS#: 475203-77-1

Mebeverine acid is a metabolite of the antispasmodic agent mebeverine.

CAIX Inhibitor S4

CAT#: 462420
CAS#: 1330061-67-0

CAIX Inhibitor S4 is an inhibitor of carbonic anhydrase IX. It is selective for CAIX over CAI and CAII but does...

Propargylcholine bromide

CAT#: 556118
CAS#: 111755-76-1 (bromide)

Propargylcholine bromide is an alkynyl derivative of choline that has a propargyl group in place of one methyl group....

JNJ-10198409

CAT#: 407889
CAS#: 627518-40-5

JNJ-10198409, also known as RWJ-540973, is an inhibitor of PDGF-BB tyrosine kinase with an IC50 value of 4.2 nM....

ML-SI3

CAT#: 556041
CAS#: 891016-02-7

ML-SI3 is a chemical compound which acts as an "antagonist" (i.e. channel blocker) of the TRPML family of calcium...

Bimiralisib free base

CAT#: 206146
CAS#: 1225037-39-7 (free base)

Bimiralisib, also known as PQR309, is an orally bioavailable pan inhibitor of phosphoinositide-3-kinases (PI3K) and...

Mavorixafor free base

CAT#: 471045
CAS#: 558447-26-0 (free base)

Mavorixafor, also known as AMD11070, AMD070, X4P-001, is an orally bioavailable and potent CXCR4 inhibitor. AMD11070...

GNF2133 HCl

CAT#: 555725
CAS#: 2561414-57-9 (HCl)

GNF2133 is a potent and selective DYRK1A inhibitor (IC50 = 6 nM). In vitro, GNF2133 is able to proliferate both...

Sirolimus (Rapamycin)

CAT#: 100766
CAS#: 53123-88-9

Sirolimus, also known as rapamycin, is a natural macrocyclic lactone produced by the bacterium Streptomyces...

ALC-0315

CAT#: 556006
CAS#: 2036272-55-4

ALC-0315 is a synthetic cationic lipid (or ionizable lipid). It is a colorless oily material, It has attracted...

PFK-158

CAT#: 206166
CAS#: 1462249-75-7

PFK-158, also known as ACT-PFK-158, is an inhibitor of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatases...

DOPA lipid

CAT#: 556116
CAS#: 108392-02-5 (sodium)

DOPA lipid, also known as 18:1 PA; 1,2-dioleoyl-sn-glycero-3-phosphate (sodium salt); PA(18:1(9Z)/18:1(9Z)); is a...

GSK5182

CAT#: 531877
CAS#: 877387-37-6 (free base)

GSK5182 is a specific inverse agonist for estrogen-related receptor γ.

Epiblastin A

CAT#: 561424
CAS#: 16470-02-3

Epiblastin A is a Casein Kinase 1 (CK1) inhibitor. Epiblastin A engages CK1 isoenzymes in cell lysate and induces...

HKI-357

CAT#: 462306
CAS#: 848133-17-5 (free base)

HKI-357 is an irreversible dual inhibitor of EGFR and ERBB2. HKI-357 suppresses EGFR autophosphorylation (at Y1068),...

MKC-3946

CAT#: 532773
CAS#: 1093119-54-0

MKC3946 is a potent and soluble IRE1α inhibitor. MKC-3946 blocks XBP1 mRNA splicing and exhibits cytotoxicity against...

NAI-N3

CAT#: 464216
CAS#: 1612756-29-2

NAI-N3 is a probe for icSHAPE (in vivo click selective 2'-hydroxyl acylation and profiling experiment). It acylates...

SM-102

CAT#: 464358
CAS#: 2089251-47-6

SM-102 is an ionizable amino lipid that has been used in combination with other lipids in the formation of lipid...

ALW-II-41-27

CAT#: 407852
CAS#: 1186206-79-0

ALW-II-41-27 is a Eph receptor tyrosine kinase inhibitor. pharmacologic inhibition of EPHA2 by the small-molecule...

NVS-PAK1-1

CAT#: 561311
CAS#: 1783816-74-9

NVS-PAK1-1 is a specific allosteric PAK1 inhibitor.

SKI-178

CAT#: 407474
CAS#: 1259484-97-3

SKI-178 is a sphingosine kinase 1 (SphK1) inhibitor (IC50 = 0.1-1.8 μM). SKI-178 induces prolonged mitosis followed...