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MedKoo Chemical Nomenclature
SR-18292 is a PGC-1α inhibitor. SR-18292 reduces blood glucose, strongly increases hepatic insulin sensitivity, and...
F1063-0967 is a novel inhibitor of dual-specificity phosphatase 26 (DUSP26), inducing apoptosis in IMR-32 cell line.
Esonarimod is an antirheumatic drug, suppressing lymphocyte activating factor activity or biosynthesis.
CAS#: 866823-63-4 (HCl)
Varenicline is a nicotinic receptor partial agonist—it stimulates nicotine receptors more weakly than nicotine itself...
UT-155 is a potent selective androgen receptor degrader (SARD), markedly reducing the activity of wild-type and...
EN4 MYC inhibitor
EN4 is a functional Covalent Ligand Targeting an Intrinsically Disordered Cysteine within MYC. EN4 functionally and...
CAS#: 869477-96-3 (HCl)
Olodaterol, also known as BI 1744, is a long acting beta-adrenoceptor agonist used as an inhalation for treating...
Tenofovir exalidex, also known as HDP-Tenofovir and CMX-157, is a novel lipid acyclic nucleoside phosphonate that...
LY-344864 free base
CAS#: 186544-26-3 (free base)
LY-344864 is a potent 5-HT1 receptor agonist.
Targocil is a antibiotic, inhibiting a late step in wall teichoic acid biosynthesis and inducing the cell wall...
Amenamevir, also known as ASP2151, is a herpes virus helicase-primase inhibitor. ASP2151 had significantly better...
CAS#: 2133832-83-2 (free base)
R-IMPP is an inhibitor of PCSK9 translation. R-IMPP stimulates uptake of LDL-C in hepatoma cells by increasing LDL-R...
CAS#: 1219925-73-1 (free base)
E6446 inhibits Toll-like receptor (TLR)7 and 9 signaling. E6446 works in a variety of human and mouse cell types and...
GSK620 is Potent, selective, and Highly Soluble Bromo and Extraterminal Domain (BET) Second Bromodomain (BD2)...
LY900009 is a small molecule inhibitor of Notch signalling via selective inhibition of the γ-secretase protein....
ZBC260, also known as BETd-260, is a potent and selective BET inhibitor or BET degrader. ZBC260 effectively...
CAS#: 1700637-55-3 (free base)
MDK-7553, also known as CD38 inhibitor 78c and Compound-78c, is a potent CD38 inhibitor. MDK-7553 has...
E-7090 is a fibroblast growth factor receptor inhibitor potentially for the treatment of solid tumors. E-7090 is a...
CAS#: 2365172-42-3 (free base)
DT2216 is a selective B-cell lymphoma extra large (BCL-XL) proteolysis-targeting chimera (PROTAC). DT2216 targets...
A-485 is a potent and selective HAT inhibitor of p300/CBP in vitro with an IC50 of 10 nM in a p300 TR-FRET assay and...
Tenalisib, also known as RP6530, is a potent and selective dual PI3Kδ/γ inhibitor that inhibited growth of B-cell...
RX-3117, also known as TV-1360 and fluorocyclopentenylcytosine, is an orally available and potent DNA synthesis...
CAS#: 2003234-63-5 (R-isomer)
R-GNE-140 a novel potent lactate dehydrogenase (LDHA) inhibitor with IC50 3nM for LDHA and 5 nM for LDHB. In MIA...
KUN56321 is a luminescent agent. The application of KUN56321 comprises: coating the film of KUN56321 onto hole...
DWN63831 is a lysyl oxidase inhbitor. DWN63831 may be useful in treatment of a variety of disorders, e.g., fibrosis,...