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WWL-154 is a serine hydrolase inhibitor. Serine hydrolases (SHs) are-one of the largest and most diverse enzyme...
CAS#: 1188910-76-0 (free base)
Agerafenib, also known as RXDX-105, CEP-32496 and AC013773, is an orally available v-raf murine sarcoma viral...
BI-135585 is a potent and selective 11β-HSD1 inhibitor. BI 135585 was safe and well tolerated over 14 days and can be...
NE52-QQ57 is an orally available GPR4 antagonist with an IC50 of 70 nM. NE 52-QQ57 significantly inhibited the...
A286982 is an inhibitor that blocks the integrin-ligand interaction between leukocyte function-associated antigen-1...
Seralutinibm, also known as PK-10571 and GB002, is a Novel Inhaled Pdgfr Kinase Inhibitor. Seralutinib demonstrates...
NVS-PAK1-1 is a specific allosteric PAK1 inhibitor.
CAS#: 1855860-24-0 (free base)
DS-1205, also known as DS-1205b, is a selective and potent AXL kinase inhibitor with IC50 of 1.3 nM. DS-1205...
HBX19818 is a selective inhibitor of USP7.
Conoidin A inactivates peroxiredoxins by covalently binding to the catalytic cysteine on the enzyme.
ERD-308 is a Highly Potent Proteolysis Targeting Chimera (PROTAC) Degrader of Estrogen Receptor (ER) ERD-308 achieves...
BDTX-189 is an orally bioavailable, irreversible, selective, small-molecule inhibitor of certain oncogenic driver,...
BI-894999 is a potent and selective BET inhibitor potentially useful for the Treatment of hematological malignancies...
Pyrimorph is a fungicide with high activity against the plant pathogen Phytophthora capsici. Pyrimorph inhibited...
AA41612 is a novel antagonist of melanopsin-mediated phototransduction.
KLH45 is a selective inhibitor of DDHD2 (DDHD domain containing 2).
WWL229 is a selective Ces3 inhibitor. It acts by inhibiting recombinant Ces3 but not Ces1f, ABHD6 or other tested...
AQX-016A, also known as NSC-741764, is a potent activator of SHIP-1.
ERDRP-0519 is an orally available polymerase inhibitor. It shows efficacy against a lethal morbillivirus infection in...
NCGC00262650 is an inhibitor of AMA1-RON2 interaction and c-Src tyrosine kinase activity.
TMP778 is a novel, potent, and selective RORıt inverse agonist. TMP778 acts potently and selectively to block mouse...
R243 is an inhibitor of CCR8 signaling and chemotaxis.
BMS-986188 is a novel Potent and Selective Positive Allosteric Modulator of the delta-Opioid Receptor.
BMS-986187 is a novel Potent and Selective Positive Allosteric Modulators of the delta-Opioid Receptor.
ML266, also known as CID-4694321, is activator of glucocerebrosidase (GCase). ML266 can serve as starting points to...