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Dimethylenastron is an inhibitor of mitotic motor kinesin Eg5 (IC50 = 200 nM). Dimethylenastron suppresses human...
BI-847325 is an orally available dual inhibitor of mitogen-activated protein kinase kinase (MEK) and Aurora kinases,...
CAS#: 2751721-40-9 (1S3R-isomer)
AZ5576 is a potent and highly selective CDK9 inhibitor. Treatment with AZ5576 inhibited growth of DLBCL cell lines in...
PF-06835919, also known as MDK1846, is a potent ketohexokinase (KHK) inhibitor. PF-06835919 is reported in patent...
CAS#: 1640282-42-3 (P-atropisomer)
Zunsemetinib, also known as ATI-450 and CDD450, is a potent MK2 Inhibitor. ATI-450 binds with high affinity to the...
CAS#: 1638178-82-1 (HCl)
HUN78821, also known as...
Rimiducid, also known as AP1903, is a lipid-permeable bivalent "dimerizer" drug that binds FKBP and induces Fas...
DIMBOA is a powerful antibiotic present in maize, wheat, and related grasses, DIMBOA was first identified in maize in...
Dilazep HCl is a coronary vasodilator with some antiarrhythmic activity.
CAS#: 1640282-44-5 (M-atropisomer)
Zunsemetinib M-atropisomer is the inactive isomer of Zunsemetinib. Zunsemetinib, also known as ATI-450 and CDD450,...
CAS#: 495399-09-2 (free)
Saroglitazar is a drug for the treatment of type 2 diabetes mellitus and dyslipidemia. It is approved for use in...
MitoBlock-6 is an Augmenter of liver regeneration (ALR) inhibitor. MitoBloCK-6 attenuated the import of Erv1...
CAS#: PLX5622 hemifumarate
PLX5562 is a highly selective brain-penetrant CSF1R inhibitor. In the 5xFAD mouse model of AD, plaques fail to form...
Dihydroethidium, also known as Hydroethidine and PD-MY 003, is a cell-permeable blue fluorescent dye. DHE-derived...
PT2385 is an orally active, small molecule inhibitor of hypoxia inducible factor (HIF)-2alpha, with potential...
Exarafenib, also known as KIN-2787. is an antineoplastic. Exarafenib has anticancer activity by suppression of...
NAI-N3 is a probe for icSHAPE (in vivo click selective 2'-hydroxyl acylation and profiling experiment). It acylates...
CAS#: 73903-17-0 (free base)
JNJ-10191584 is a drug which acts as a potent and selective antagonist at the histamine H4 receptor. It has...
TUG-469 is a potent free fatty acid 1 receptor agonist. TUG-469 showed a 1.7- to 3.0-times higher potency in vitro at...
CP-447697 is a small molecule C5aR antagonist.
YHO-13177 is a potent and specific inhibitor of breast cancer resistance protein (BCRP/ABCG2). YHO-13177 potentiated...
JTE-013 is a potent, selective sphingosine-1-phosphate 2 (S1P2) receptor antagonist that binds to the human and rat...
CAS#: 2110426-27-0 (free base)
JNJ63576253, also known as TRC253, is a potent and orally active androgen receptor antagonist. TRC253 specifically...
CAS#: 1346528-50-4 (free base); 1346528-52-6 (mono HCl salt); 1346528-51-5 (2HCl salt)
JNJ-42165279 is a potent and selective fatty acid amide hydrolase (FAAH) inhibitor. JNJ-42165279 covalently...
JNJ-42153605 is a potent and selective mGlu2 receptor PAM with an acceptable pharmacokinetic profile in rodent and...