GLUT inhibitor-1
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MedKoo CAT#: 126528

CAS#: 2421141-40-2

Description: GLUT inhibitor-1 is a potent and orally active inhibitor of glucose transporters, targeting both GLUT1 and GLUT3, with IC50s of 242 nM and 179 nM, respectively.


Chemical Structure

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GLUT inhibitor-1
CAS# 2421141-40-2

Theoretical Analysis

MedKoo Cat#: 126528
Name: GLUT inhibitor-1
CAS#: 2421141-40-2
Chemical Formula: C32H35N7O2
Exact Mass: 549.29
Molecular Weight: 549.679
Elemental Analysis: C, 69.92; H, 6.42; N, 17.84; O, 5.82

Price and Availability

Size Price Availability Quantity
50mg USD 2650 2 Weeks
100mg USD 3650 2 Weeks
1g USD 6950 2 Weeks
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Synonym: GLUT inhibitor 1; GLUT inhibitor-1; GLUT inhibitor1

IUPAC/Chemical Name: 2-(3-(4-((4-(1H-pyrazol-4-yl)phenyl)amino)-6-cyclobutyl-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-2-yl)phenoxy)-N-(1-methylcyclopropyl)acetamide

InChi Key: IXZVJTRRPOHKJF-UHFFFAOYSA-N

InChi Code: InChI=1S/C32H35N7O2/c1-32(13-14-32)38-29(40)20-41-26-7-2-4-22(16-26)30-36-28-12-15-39(25-5-3-6-25)19-27(28)31(37-30)35-24-10-8-21(9-11-24)23-17-33-34-18-23/h2,4,7-11,16-18,25H,3,5-6,12-15,19-20H2,1H3,(H,33,34)(H,38,40)(H,35,36,37)

SMILES Code: O=C(COC1=CC=CC(C2=NC(CCN(C3CCC3)C4)=C4C(NC5=CC=C(C6=CNN=C6)C=C5)=N2)=C1)NC7(CC7)C

Appearance: To be determined

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 549.68 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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