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Inavolisib, also known as GDC-0077, is a potent and selective PI3K inhibitor. GDC-0077 blocks an enzyme involved in...
JZL184 is highly selective, and potent MAGL inhibitor ( monoacylglycerol lipase inhibitor). JZL184 improves behavior...
JNJ-40411813, also known as ADX71149, is a positive allosteric modulator of the mGlu2 receptor. JNJ-40411813 acts as...
Gloxazone is an effective but toxic anaplasmacide.
Moracin M is a phosphodiesterase-4 inhibitor isolated from Morus alba. Moracin M has anti-inflammatory activity....
TGP-377421, also known as TGP-377/421 and Targapre-miR-377/421, is a potent miR-377 and miR-421 inhibitor that binds...
FEMA-4809 is a highly potent TRPM8 agonist that is used as a cooling agent.
ZINC30303842 is a NSD2-PWWP1 antagonist,
WAY-111543 is a bioactive chemical.
Velufenacin is a muscarinic receptor antagonist.
CT52923, also known as KN734, is a platelet-derived growth factor receptor (PDGFR) inhibitor. CT52923 exhibited...
SR18662 is an optimized anticancel agent based on ML264. SR18662 Efficiently Inhibits the Growth of Colorectal...
MMRi62 is an MDM4-degrader and apoptosis inducer in leukemia cells. MMRi62 targets MDM4 for degradation and induces...
DXD is an Exatecan derivative and topoisomerase I inhibitor. DXD can be used to make antibody drug conjugate such as...
BMS193885 free base
CAS#: 186185-03-5 (free base)
BMS-193885 is a potent, competitive neuropeptide (NPY) Y1 antagonist (Ki = 3.3 nM, IC50 = 5.9 nM) that displays > 47,...
DWN63831 is a lysyl oxidase inhbitor. DWN63831 may be useful in treatment of a variety of disorders, e.g., fibrosis,...
MC-DM is a Maytansine derative and a DM1 molecule with an reactive linker MC. MC-DM1 is a useful precursor to make...
DTP3 is a selective GADD45β/MKK7 inhibitor, which inhibits cancer-selective NF-κB survival pathway. DTP3 specifically...
SR-18292 is a PGC-1α inhibitor. SR-18292 reduces blood glucose, strongly increases hepatic insulin sensitivity, and...
DTHIB is a direct and selective heat shock factor 1 (HSF1) inhibitor with a Kd of 160 nM. DTHIB physically engages...
CAS#: 2375564-55-7 (free base)
ACBI1 is a potent and cooperative degrader of SMARCA2, SMARCA4 and PBRM1. ACBI1 induced anti-proliferative effects...
GSK215 is a potent, selective, FAK-degrading Proteolysis Targeting Chimera (PROTAC) based on a binder for the VHL E3...
Antrodin A, also known as AdA and Camphorataanhydride A, is one of the main active ingredients in the solid-state...
Rimiducid, also known as AP1903, is a lipid-permeable bivalent "dimerizer" drug that binds FKBP and induces Fas...
VB124 is a novel, highly potent MCT4 inhibitor that mitigated hypertrophy in cultured cardiomyocytes and in mice.