Newest Products

PLX5622 fumarate

CAT#: 555654
CAS#: 2749102-07-4 (fumarate)

PLX5562 is a highly selective brain-penetrant CSF1R inhibitor. In the 5xFAD mouse model of AD, plaques fail to form...

NAI-N3

CAT#: 464216
CAS#: 1612756-29-2

NAI-N3 is a probe for icSHAPE (in vivo click selective 2'-hydroxyl acylation and profiling experiment). It acylates...

PI-103

CAT#: 202235
CAS#: 371935-74-9 (free base)

PI-103 is a potent, cell-permeable, ATP-competitive inhibitor of phosphatidylinositol 3-kinase (PI3K) family members...

ISCK03

CAT#: 407436
CAS#: 945526-43-2

ISCK03 is a potent c-kit inhibitor. ISCK03 inhibits SCF/c-kit signaling in 501mel human melanoma cells and...

JNJ-40411813

CAT#: 526853
CAS#: 1127498-03-6

JNJ-40411813, also known as ADX71149, is a positive allosteric modulator of the mGlu2 receptor. JNJ-40411813 acts as...

HTH-01-015

CAT#: 406832
CAS#: 1613724-42-7

HTH-01-015 is a potent and selective inhibitor of NUAK1 (IC50 = 100 nM) and does not affect the activity of a panel...

BRD0639

CAT#: 465267
CAS#: 2760881-74-9

BRD0639 is a potent PRMT5 inhibitor. BRD0639 engages the target in cells, disrupts PRMT5-RIOK1 complexes, and reduces...

JNJ-10198409

CAT#: 407889
CAS#: 627518-40-5

JNJ-10198409, also known as RWJ-540973, is an inhibitor of PDGF-BB tyrosine kinase with an IC50 value of 4.2 nM....

HMN-176

CAT#: 201480
CAS#: 173529-10-7

HMN-176 is an active metabolite of the synthetic antitumor compound HMN-214. HMN-176 shows potent cytotoxicity toward...

HJC0152

CAT#: 533009
CAS#: 1420290-99-8

HJC0152 is a signal transducer and activator of transcription 3 (STAT3) inhibitor against human head and neck...

Hibifolin

CAT#: 330184
CAS#: 55366-56-8

Hibifolin is a flavonol glycoside that prevents beta-amyloid-induced neurotoxicity in vitro. Hibifolin prevents...

HA14-1

CAT#: 201460
CAS#: 65673-63-4

HA14-1 is a potent Bcl-2 inhibitor with potential anticancer activity. HA14-1 induces apoptosis in various human...

GW-4869 HCl

CAT#: 555211
CAS#: 6823-69-4 (HCl)

GW-4869 is a cell-permeable, non-competitive inhibitor of neutral sphingomyelinases (IC50 = 1 μM). It inhibits...

JNJ 63533054

CAT#: 523108
CAS#: 1802326-66-4

JNJ 63533054 is a potent and selective GPR139 agonist (EC50 = 16 nM) that is brain and cell penetrant. JNJ 63533054...

Eleclazine HCl

CAT#: 563723
CAS#: 1448754-43-5 (HCl)

Eleclazine HCl is a novel late Na+ current inhibitor.

TT01001

CAT#: 562621
CAS#: 1022367-69-6

TT01001 is a mitoNEET ligand. It acts by improving diabetes and ameliorates mitochondrial function in db/db mice.

FHN88734

CAT#: 556139
CAS#: 153088-73-4

FHN88734, also known as Z-Asp-CH2-DCB and PASE-1 INHIBITOR V, is an inhibitor of ICE/Ced-3 family proteases. This...

DDD85646

CAT#: 530985
CAS#: 1215010-55-1

DDD85646 is a T. brucei N-myristoyltransferase (TbNMT) with an apparent Ki value of 1.44 nM. DDD85646 has potent...

Elinogrel

CAT#: 319823
CAS#: 936500-94-6 (free base)

Elinogrel, also known as PRT 060128, is P2Y12 inhibitor. Similarly to ticagrelor and in contrast to clopidogrel,...

PhTx-74 HCl

CAT#: 555147
CAS#: 1227301-51-0 (HCl)

Philanthotoxin-74, also known as PhTx-74, is a synthetic analog of the naturally-occurring wasp venom toxin...

AGX51

CAT#: 533417
CAS#: 330834-54-3

AGX51 is a first-in-class pan-Id antagonist, inhibiting pathologic ocular neovascularization and the Id1-E47...

WUN55267

CAT#: 556135
CAS#: 874755-26-7

WUN55267, also known as GPR40/FFAR1 modulator 1, is an agonist and an allosteric modulator for Gq-coupled free fatty...

Cathepsin Inhibitor 1

CAT#: 562868
CAS#: 225120-65-0

Cathepsin Inhibitor 1 is a pan-inhibitor of Cathepsin (L, L2, S, K, B).

Bacteriopheophytin

CAT#: 556134
CAS#: 17453-58-6

Bacteriopheophytin, also known as Bacteriopheophytin a, is a Pigment which is the degradation product of...

FGFR4-IN-1

CAT#: 406965
CAS#: 1708971-72-5

FGFR4-IN-1 is a potent and selective FGFR4 inhibitor. FGFR4 may be a novel therapeutic target for gastric cancer.