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406135
SB505124
featured
SB505124:  SB505124 is a selective inhibitor of transforming growth factor-β type I receptor (ALK5, …
406249
PF-03671148
PF-03671148 is a potent ALK inhibitor. PF-03671148 inhibits the expression of fibrotic genes and pro…
401002
A83-01
featured
A-83-01 is an ALK inhibibitor. It was found that A-83-01 inhibited the transcriptional activity indu…
206013
Ensartinib free base
featured
Ensartinib, also known as X-396, is an orally available small molecule inhibitor of the receptor tyr…
201310
Etalocib
new
featured
Etalocib, also known as LY293111 and VML295, is a novel diaryl ether carboxylic acid derivative, is …
206055
CEP-37440
featured
CEP-37440 is an orally available dual kinase inhibitor of the receptor tyrosine kinase anaplastic ly…
401213
CEP-28122
featured
CEP-28122 is a highly potent and selective orally active ALK inhibitor with a favorable pharmaceutic…
206039
AZD-3463
featured
AZD-3463 is a potent ALK/IGF1R inhibitor with potential anticancer activity. AZD3463 inhibits neurob…
204450
ASP-3026
featured
ASP3026 is a novel and selective inhibitor for the ALK kinase. ASP3026 potently inhibited ALK kinase…
205765
Brigatinib-analog
featured
Brigatinib-analog is an orally active, potent and selective anaplastic lymphoma kinase (ALK) and th…
406626
CEP-14513
CEP-14513 is a potent ALK inhibitor. CEP-14513 displayed potent ALK inhibitory activity in both in v…
406625
CEP-14083
CEP-14083 is a potent ALK inhibitor that has shown activity in an NPM/ALK–carrying T-cell lymphoma …
406614
GW6604
featured
GW6604 is a potent and selective ALK-5 inhibitor with potent anticancer activity. GW6604 is also a T…
206139
Gilteritinib
featured
Gilteritinib, also known as ASP2215, is a potent FLT3/AXL inhibitor, which showed potent antileukemi…
406533
Lorlatinib (PF-06463922)
featured
Lorlatinib, also known as PF-06463922, is an orally available, ATP-competitive inhibitor of the rec…
401475
GSK1838705A
featured
GSK1838705A is a small-molecule kinase inhibitor that inhibits IGF-IR and IR (insulin receptor) with…
202222
Crizotinib
featured
Crizotinib, also known as PF-02341066, is an orally bioavailable agent belonging to the class of c-m…
205511
Ceritinib free base
featured
Ceritinib, also known as LDK378, is a selective inhibitor of ALK1, a target found in metastatic non-…
206181
Entrectinib
new
featured
Entrectinib, also known as RXDX-101 and NMS-E628, is an oral small molecule inhibitor of TrkA, TrkB …
205799
Alectinib free base
featured
Alectinib, also known as AF802, or CH5424802 or RO5424802, is a potent, selective, and orally availa…
202045
TAE684
featured
TAE684, also known as NVP-TAE684, is a highly potent and selective small-molecule ALK inhibitor, whi…