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FLT3 Products

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406544
UNC-2025
featured
UNC-2025 is a novel potent and highly orally bioavailable Mer/FLT3 dual inhibitor, capable of inhibi…
406536
TTT-3002
TTT-3002 is a tyrosine kinase inhibitor (TKI) that is one of the most potent FLT3 inhibitors discove…
406289
TCS-359
featured
TCS-359 is a potent inhibitor of FLT3 with IC50 of 42 nM.
406220
SU11657
SU11657 is a FLT3 inhibitor and also a multireceptor tyrosine kinase inhibitor (primarily vascular e…
406219
Chloro-SU5416
featured
Chloro-SU5416, also known as Chloro-Semaxanib, is a potent and selective FLT3 inhibitor and RET inh…
401915
SIM010603
SIM010603 is a structurally novel, oral, multi-targeted receptor tyrosine kinase inhibitor. SIM01060…
406185
LBW242
LBW242 is a Smac mimetic, and potent IAP inhibitor. LBW242 is effective against mutant FLT3 at doses…
406114
KRC-108
KRC-108 is a multiple kinase inhibitor. KRC-108 is a potent inhibitor of Ron, Flt3 and TrkA as well …
406201
JNJ-28312141
JNJ-28312141 is an orally active CSF1R inhibitor (Colony-stimulating factor-1 receptor, CRF1R) and a…
406205
GTP-14564
featured
GTP-14564 is a specific kinase inhibitor for ITD-FLT3. GTP-14564 inhibited the growth of interleukin…
406207
FI-700
FI-700 is a novel and potent FLT3 inhibitor with promising antileukemia activity. FI-700 showed a po…
406204
CGP52421
CGP52421 is a FLT3 inhibitor, which is also an metabolite of midostaurin (PKC412).
406488
BPR1J-340
BPR1J-340 is a potent and selective FLT3 inhibitor with potential anticancer activity. BPR1J-340 was…
406217
AUZ454
featured
AUZ454 is a potent and selective Type II FLT3 inhibitor. AUZ454 is able to override drug resistanc…
406218
ATH686
ATH686 is a FLT3 inhibitor.
406211
AST487
featured
AST487, also known as NVP-AST487, is a RET kinase inhibitor/FLT3 inhibitor. The RET kinase has emerg…
406521
FLX925 (AMG-925)
new
featured
FLX925, also known as AMG-925, is a potent and selective type 1 inhibitor of FLT3 that retains its …
406216
AHL196
AHL196 is a FLT3 inhibitor.
406215
AFG210
AFG210 is a novel first-generation “type II” FLT3 inhibitor.
406214
AFG206
AFG206 is the novel first-generation "type II" FLT3 inhibitor.
406213
AAE871
AAE871 is a type I FLT3 inhibitor.
205665
XL999
XL999, a Spectrum Selective Kinase Inhibitor(TM) (SSKIs), is a potent inhibitor of key RTKs implicat…
202790
Tandutinib
featured
Tandutinib, also known as MLN 518, is a piperazinyl quinazoline receptor tyrosine kinase inhibitor w…
200072
Quizartinib HCl
featured
Quizartinib, also known as AC220 and AC010220, is a highly potent FMS-like receptor tyrosine kinase-…
202571
Pacritinib (SB1518)
featured
Pacritinib, also known as SB1518, is an orally bioavailable inhibitor of Janus kinase 2 (JAK2) and t…
205625
SB1578
SB1578, also known as ONX-0805, is a novel, orally bioavailable JAK2 inhibitor with specificity for …
205925
LY2457546
LY2457546 is a potent and orally bioavailable inhibitor of multiple receptor tyrosine kinases involv…
200060
Linifanib (ABT-869)
featured
Linifanib, also known as ABT-869, is an orally bioavailable, small-molecule receptor tyrosine kinas…
201730
Lestaurtinib
featured
Lesraurtinib, also known as CEP701; KT 5555; SP 924, is an orally bioavailable indolocarbazole deriv…
206213
KW-2449
featured
KW-2449 is a novel multikinase inhibitor, which suppresses the growth of leukemia cells with FLT3 mu…
200421
AZD-1152HQPA
featured
AZD-1152 HQPA, also known as AZD-2811, is a potent and selective Aurora B inhibitor (IC50 of 0.37 nM…
205942
AKN-028
AKN-028, the FLT3/KIT kinase inhibitor, is an orally bioavailable protein tyrosine kinase inhibitor …
205802
4SC-203
new
featured
4SC-203 is a multikinase inhibitor with potential antineoplastic activity. Multikinase inhibitor 4SC…
202320
Ponatinib
featured
Ponatinib is an orally bioavailable multitargeted receptor tyrosine kinase (RTK) inhibitor with pote…
401120
AZD-2932
featured
AZD-2932 is a high affinity inhibitor of VEFGR-2 and PDGFR. AZD-2932 has a balanced ~ 1:1 ratio of a…
406593
G-749
featured
G-749 is a novel FLT3 inhibitor that showed potent and sustained inhibition of the FLT3 wild type an…
202893
Fedratinib
featured
Fedratinib, also known as TG101348 and SAR302503, is a JAK2 inhibitor, is also an orally bioavailab…
201950
Amuvatinib
featured
Amuvatinib, also known as MP-470, is an orally bioavailable synthetic carbothioamide with potential …
200760
Dovitinib lactate
featured
Dovitinib, also known as TKI-258 or CHIR-258, is an orally bioavailable FGFR3 inhibitor, which stron…
206139
Gilteritinib
featured
Gilteritinib, also known as ASP2215, is a potent FLT3/AXL inhibitor, which showed potent antileukemi…
205642
Zotiraciclib free base
featured
Zotiraciclib, also known as TG02 and SB1317, is a novel small molecule potent CDK/JAK2/FLT3 inhibit…
202710
SU14813
featured
SU14813 is an oral, multitargeted tyrosine kinase inhibitor (TKI) targeting vascular endothelial gro…
205710
SGI-1776
featured
SGI-1776 is a small-molecule pan-Pim protein kinase inhibitor with potential antineoplastic activity…
200595
Cabozantinib (free base)
featured
Cabozantinib, also known as XL-184 and BMS-907351, is the s-malate salt form of cabozantinib, an or…
401161
BPR1J-097
featured
BPR1J-097 is a novel small molecule FLT-3 inhibitor with promising in vivo anti-tumour activities. B…
100790
Sunitinib malate
featured
Sunitinib, also known as SU11248, is the orally bioavailable malate salt of an indolinone-based tyro…
206178
Pexidartinib (PLX3397)
featured
Pexidartinib, also know as PLX-3397, is a CSF1R inhibitor with IC50 of 20 nM in development by Plex…
200496
Nintedanib
featured
Nintedanib, also known as BIBF 1120, is an orally bioavailable inhibitor of vascular endothelial gro…