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Vaneprim is an antibacterial agent.
CAS#: 2561414-57-9 (HCl)
GNF2133 is a potent and selective DYRK1A inhibitor (IC50 = 6 nM). In vitro, GNF2133 is able to proliferate both...
Icenticaftor, also known as QBW251 is a Cystic Fibrosis Transmembrane Conductance Regulator Potentiator with Clinical...
GLPG2938 is an antagonists of sphingosine-1-phosphate (S1P) receptor for prophylaxis and/or treatment of diseases...
CAS#: 1883545-52-5 (TFA)
MM-102 is a Potent WDR5/MLL interaction inhibitor. The MM-102 compound prevents the interaction between mixed lineage...
MLS1547 is a highly efficacious D2 dopamine receptor (D2R) G protein-biased agonist that does not recruit β-arrestin,...
BAY-8400 is a novel selective inhibitor of DNA-PK. In in vitro studies, BAY-8400 showed synergistic activity of...
CAS#: 1782573-78-7 (2HCl)
MLN-120B is a potent and effective inhibitor of IκB kinase beta subunit (IKKβ) with IC50 value of 20 μM. MLN-120B...
ML-7 is a MLCK inhibitor. ML-7 inhibits smooth muscle myosin light chain kinase (MLCK) with a Ki value of 0.3 µM....
BIT-225 is a NCp7 zinc finger inhibitor potentially for the treatment of HCV infection and HIV infection. BIT225...
ML364 is a small molecule inhibitor of the deubiquitinase USP2 with potential anticancer activity. ML364 has an IC50...
Eliapixant, also known as BAY 1817080, is a P2X3 receptor antagonist. Eliapixant is both highly potent and selective...
CYM51010, also known as CID23723457 and ML335, is a biased ligand of μ-opioid receptor – δ-opioid receptor...
MRTX1719 is a potent and selective binder to the PRMT5•MTA complex and selectively inhibits PRMT5 activity in...
ML-329 is an inhibitor of the microphthalmia-associated transcription factor (MITF) pathway with an IC50 value of 1.2...
ML-324, also known as CID-44143209, is a potent JMJD2 demethylase inhibitor with demonstrated antiviral...
ML311, also known as EU-5346, is a potent and selective inhibitor of the Protein-Protein Interaction of Mcl-1 and...
ML277 is a potent activator of KCNQ1 (Kv7.1) channels with >100-fold selectivity versus KCNQ2 and KCNQ4 and no...
ML266, also known as CID-4694321, is activator of glucocerebrosidase (GCase). ML266 can serve as starting points to...
ML-254, also known as VU0430644; is Positive Allosteric Modulators (PAMs) of mGlu5 with Competitive MPEP-Site...
ML239 is a potent and selective inhibitor of breast cancer stem cells. ML239 was best-in-class with an IC(50)= 1.18...
Rilzabrutinib, also known as PRN1008, is a reversible covalent, selective and oral active inhibitor of Bruton’s...
CAS#: 2070015-10-8 (HCl)
ML204 is a novel and potential TRPC4 Channel inhibitor. ML204 inhibited TRPC4β-mediated intracellular Ca(2+) rise...
ML-193, also known as CID 1261822, is a potent antagonist of GPR55 (IC50 = 221 nM).
ML192, also known as MLS000526305 and CID1434953, is a selective ligands for GPR55. The orphan G protein coupled...