Newest Products

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KL-11743

CAT#: 208129
CAS#: 1369452-53-8

KL-11743 is a representative compound that blocks glucose metabolism, triggering an acute collapse in NADH pools and a striking accumulation of aspart…
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CCT373566

CAT#: 466270
CAS#: 2378853-66-6

CCT373566 is a highly potent BCL6 degrader (IC50 =0.7 nM) suitable for sustained depletion of BCL6 in vivo. CCT373566 showed modest in vivo efficacy i…
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HQ461

CAT#: 408174
CAS#: 1226443-41-9 (free base)

HQ461 is a Molecular-glue degrader. HQ461 acts by promoting an interaction between CDK12 and DDB1-CUL4-RBX1 E3 ubiquitin ligase, leading to polyubiqui…
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VUN73874

CAT#: 556087
CAS#: 732973-87-4

VUN73874, also known as GOT1 inhibitor 2c, is a glutamate-​oxaloacetate transaminase 1 (GOT1)​ inhibitor. This compound was first reported in Bioorg …
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CUN43389

CAT#: 556086
CAS#: 1807943-38-9

CUN43389, also known as SMS1-IN-1 and SAPA1j, is a SAPA inhibitor (sphingomyelin synthase 1 inhibitor). SAPA 1j was found to be the most potent SMS1 i…
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VV116

CAT#: 556084
CAS#: 2647442-33-7,

VV116, also known as JT001, is an oral drug candidate of nucleoside analog against SARS-CoV-2. VV116 is a deuterated, tri-isobutyrate ester prodrug of…
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Dov-Val-Dil-OH TFA

CAT#: 408173
CAS#: 133120-90-8 (TFA)

Dov-Val-Dil-OH is a useful chemical intermediate for synthesis of auristatin-related compounds, such as Monomethyl auristatin E (MMAE), Auristatins a…
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DL-AP-3

CAT#: 556082
CAS#: 20263-06-3

DL-AP-3, or AP-3 is a Potent metabotropic glutamate receptor antagonist.
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DPPS

CAT#: 471172
CAS#: 145849-32-7

DPPS is a form of phosphatidylserine (PS), an anionic phospholipid.
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Phthalazinone pyrazole

CAT#: 408172
CAS#: 880487-62-7

Phthalazinone pyrazole is a potent inhibitor of Aurora A kinase (IC50 = 31 nM). Phthalazinone pyrazole displays good pharmacological profiles with sig…
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MS-177

CAT#: 466223
CAS#: 2225938-86-1

MS177 is an effective and fast-acting EZH2 degrader. MS177 is a PROTAC that consists of a CRBN ligand, linker, and a potent enzymatic EZH2 inhibitor C…
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VY-3-135

CAT#: 556081
CAS#: 1824637-41-3

VY-3-135 is a potent ACSS2 inhibitor. VY-3-135 acts as a transition-state mimetic to block ACSS2 activity in vitro and in vivo. Pharmacologic inhibit…
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NAN190 free base

CAT#: 577955
CAS#: 102392-05-2 (free base)

NAN-190 is a mixed antagonist and partial agonist of the serotonin (5-HT) receptor subtype 5-HT1A. NAN-190 potentiates the circadian response to light…
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JTE-051

CAT#: 466148
CAS#: 1309784-09-5

JTE-051 is a novel inhibitor of interleukin-2-inducible T cell kinase (ITK), suppressing the signal to activate T cells related to immune response.
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BAY-179

CAT#: 471139
CAS#: 2764880-87-5

BAY-179 is a potent, selective, and species cross-reactive OXPHOS complex I inhibitor.
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DT2216-isomer

CAT#: 408171
CAS#: DT2216-isomer

DT2216-isomer is an isomer of DT2216. Compared to DT-2216, DT2216-isomer has a S-chiral carbon which links to the nitrogen atom of the aniline group.…
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Spliceostatin A

CAT#: 333084
CAS#: 391611-36-2

Spliceostatin A is a potent splicing inhibitor. Spliceostatin A (SSA) causes cell cycle arrest at G1 and G2/M phases. Spliceostatin A treatment inhibi…
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Sibiromycin

CAT#: 333083
CAS#: 12684-33-2

Sibiromycin is a natural compound with antitumor activity. Sibiromycin is also a potent antitumor antibiotic that binds covalently to DNA in the minor…
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Gramicidin S TFA

CAT#: 333082
CAS#: 113-73-5 (free base)

Gramicidin S (GS), also known as Gramicidin soviet, is an antibiotic. GS reduces the cell number of planktonic cells within 20-40 min at a concentrati…
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Gramicdin A

CAT#: 333081
CAS#: 11029-61-1

Gramicidin A is a peptide component of gramicidin, an antibiotic mixture originally isolated from B. brevis.
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RY785

CAT#: 556675
CAS#: 1393748-80-5

RY785 is a selective inhibitor of Kv2.1 voltage-gated potassium channels (IC50 = 0.05 µM) that does not affect Cav2 calcium channels.
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JYN42346

CAT#: 556674
CAS#: 1903742-34-6

JYN42346, also known as Complement factor D-IN-2, is an inhibitor of complement factor D. JYN42346 targets factor D and inhibits the complement cascad…
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THI0019

CAT#: 556072
CAS#: 1378532-99-0

THI0019 is an agonist of very late antigen-4 (VLA-4) integrin that induces progenitor cell adhesion. THI0019 greatly enhanced the adhesion of cultured…
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Micafungin sodium

CAT#: 577845
CAS#: 208538-73-2 (sodium)

Micafungin sodium a cyclic hexapeptide echinocandin lipopeptide.
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Asulacrine free base

CAT#: 330780
CAS#: 80841-47-0 (free base)

Asulacrine, also known as CI-921; NSC-343499; SN-21407, is a topoisomerase ll inhibitor with antineoplastic properties. Asulacrine inhibits the enzym…