WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 123024
CAS#: 2863607-71-8
Description: 1-Hex-GlcNAlk is a metabolic chemical reporter (MCR) for studying glycoproteins and glycosylation.
MedKoo Cat#: 123024
Name: 1-Hex-GlcNAlk
CAS#: 2863607-71-8
Chemical Formula: C17H27NO7
Exact Mass: 357.18
Molecular Weight: 357.4
Elemental Analysis: C, 57.13; H, 7.61; N, 3.92; O, 31.34
Synonym: 1-Hex-GlcNAlk; 1Hex-GlcNAlk; 1-Hex GlcNAlk
IUPAC/Chemical Name: (2S,3R,4R,5S,6R)-4,5-Dihydroxy-6-(hydroxymethyl)-3-(pent-4-ynamido)tetrahydro-2H-pyran-2-yl hexanoate
InChi Key: PJQZXSANZZIQIK-YFTGLANFSA-N
InChi Code: InChI=1S/C17H27NO7/c1-3-5-7-9-13(21)25-17-14(18-12(20)8-6-4-2)16(23)15(22)11(10-19)24-17/h2,11,14-17,19,22-23H,3,5-10H2,1H3,(H,18,20)/t11-,14-,15-,16-,17+/m1/s1
SMILES Code: CCCCCC(O[C@H]1[C@H](NC(CCC#C)=O)[C@@H](O)[C@H](O)[C@@H](CO)O1)=O
Appearance: To be determined
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 357.4 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Pedowitz NJ, Jackson EG, Overhulse JM, McKenna CE, Kohler JJ, Pratt MR. Anomeric Fatty Acid Functionalization Prevents Nonenzymatic S-Glycosylation by Monosaccharide Metabolic Chemical Reporters. ACS Chem Biol. 2021 Oct 15;16(10):1924-1929. doi: 10.1021/acschembio.1c00470. Epub 2021 Jul 20. PMID: 34282887; PMCID: PMC8865331.
