Rosiglitazone potassium
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MedKoo CAT#: 112061

CAS#: 316371-84-3 (potassium)

Description: Rosiglitazone activates PPARγ1 and PPARγ2 and selectively activates chimeras containing the ligand-binding domains (LBDs) of PPARγ over PPARα and PPARδ in a cell-based reporter assay at 10 mM and can induce differentiation of C3H10T1/2 stem cells into adipocytes when used at a concentration of 1 µM.

Chemical Structure

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Rosiglitazone potassium
CAS# 316371-84-3 (potassium)
Instruction

Theoretical Analysis

MedKoo Cat#: 112061
Name: Rosiglitazone potassium
CAS#: 316371-84-3 (potassium)
Chemical Formula: C18H18KN3O3S
Exact Mass: 0.00
Molecular Weight: 395.520
Elemental Analysis: C, 54.66; H, 4.59; K, 9.89; N, 10.62; O, 12.14; S, 8.11

Price and Availability

Size Price Availability Quantity
10mg USD 285 2 Weeks
50mg USD 650 2 Weeks
100mg USD 950 2 Weeks
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Related CAS #: 155141-29-0 (maleate)   122320-73-4 (free base)   316371-84-3 (potassium)  

Synonym: Rosiglitazone (potassium salt); Rosiglitazone K; Rosiglitazone (K)

IUPAC/Chemical Name: potassium 5-(4-(2-(methyl(pyridin-2-yl)amino)ethoxy)benzyl)-2,4-dioxothiazolidin-3-ide

InChi Key: RWOGCLSZSSKLEN-UHFFFAOYSA-M

InChi Code: InChI=1S/C18H19N3O3S.K/c1-21(16-4-2-3-9-19-16)10-11-24-14-7-5-13(6-8-14)12-15-17(22)20-18(23)25-15;/h2-9,15H,10-12H2,1H3,(H,20,22,23);/q;+1/p-1

SMILES Code: CN(C1=NC=CC=C1)CCOC2=CC=C(C=C2)CC3SC([N-]C3=O)=O.[K+]

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
Ethanol 2.0 5.06
H2O 1.0 2.53

Preparing Stock Solutions

The following data is based on the product molecular weight 395.52 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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