WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 555366

CAS#: 676596-65-9

Description: 1-Azakenpaullone is an analog of kenpaullone that inhibits glycogen synthase kinase 3β (GSK3β) more potently (IC50 = 18 nM) than CDK1/cyclin B or CDK5/p25 (IC50s = 2.0 and 4.2 µM, respectively).

Chemical Structure

CAS# 676596-65-9

Theoretical Analysis

MedKoo Cat#: 555366
Name: 1-Azakenpaullone
CAS#: 676596-65-9
Chemical Formula: C15H10BrN3O
Exact Mass: 327.0007
Molecular Weight: 328.169
Elemental Analysis: C, 54.90; H, 3.07; Br, 24.35; N, 12.80; O, 4.88

Price and Availability

Size Price Availability Quantity
5.0mg USD 450.0 2 Weeks
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Synonym: 1-Azakenpaullone

IUPAC/Chemical Name: 9-bromo-7,12-dihydro-pyrido[3',2':2,3]azepino[4,5-b]indol-6(5H)-one


InChi Code: InChI=1S/C15H10BrN3O/c16-8-3-4-11-9(6-8)10-7-13(20)18-12-2-1-5-17-15(12)14(10)19-11/h1-6,19H,7H2,(H,18,20)

SMILES Code: O=C(NC1=CC=CN=C12)CC3=C2NC4=C3C=C(Br)C=C4

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

Preparing Stock Solutions

The following data is based on the product molecular weight 328.169 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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