WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 563570
CAS#: 312631-87-1
Description: 10074-A4 is a Myc-Max-specific inhibitor.
MedKoo Cat#: 563570
Name: 10074-A4
CAS#: 312631-87-1
Chemical Formula: C18H14Cl2N2O3S
Exact Mass: 408.0102
Molecular Weight: 409.28
Elemental Analysis: C, 52.82; H, 3.45; Cl, 17.32; N, 6.84; O, 11.73; S, 7.83
Synonym: 10074-A4; 10074 A4; 10074A4;
IUPAC/Chemical Name: 3-[3-(3,6-Dichloro-carbazol-9-yl)-2-hydroxy-propyl]-thiazolidine-2,4-dione
InChi Key: SCNHANGMZXFWOH-UHFFFAOYSA-N
InChi Code: InChI=1S/C18H14Cl2N2O3S/c19-10-1-3-15-13(5-10)14-6-11(20)2-4-16(14)21(15)7-12(23)8-22-17(24)9-26-18(22)25/h1-6,12,23H,7-9H2
SMILES Code: O=C(N1CC(O)CN2C3=C(C4=C2C=CC(Cl)=C4)C=C(Cl)C=C3)SCC1=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.03.00
The following data is based on the product molecular weight 409.28 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Jin F, Yu C, Lai L, Liu Z. Ligand clouds around protein clouds: a scenario of ligand binding with intrinsically disordered proteins. PLoS Comput Biol. 2013;9(10):e1003249. doi: 10.1371/journal.pcbi.1003249. Epub 2013 Oct 3. PubMed PMID: 24098099; PubMed Central PMCID: PMC3789766.
