Pipratecol

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 592588

CAS#: 15534-05-1 (free base)

Description: Pipratecol is substituted thienoimidazole. It is the H+/K(+)-ATPase inhibitor.

Chemical Structure

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Pipratecol
CAS# 15534-05-1 (free base)
Instruction

Theoretical Analysis

MedKoo Cat#: 592588
Name: Pipratecol
CAS#: 15534-05-1 (free base)
Chemical Formula: C19H24N2O4
Exact Mass: 344.17
Molecular Weight: 344.410
Elemental Analysis: C, 66.26; H, 7.02; N, 8.13; O, 18.58

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Related CAS #: 15622-04-5 (2HCl)   15534-05-1 (free base)  

Synonym: Pipratecol

IUPAC/Chemical Name: alpha-(3,4-Dihydroxyphenyl)-4-(2-methoxyphenyl)-1-piperazineethanol

InChi Key: QESTYTNSJJTQCI-UHFFFAOYSA-N

InChi Code: InChI=1S/C19H24N2O4/c1-25-19-5-3-2-4-15(19)21-10-8-20(9-11-21)13-18(24)14-6-7-16(22)17(23)12-14/h2-7,12,18,22-24H,8-11,13H2,1H3

SMILES Code: OC(C1=CC=C(O)C(O)=C1)CN2CCN(C3=CC=CC=C3OC)CC2

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 344.41 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Cattaneo M, D'Angelo A, Mannucci PM, Pareti F, Vanasia S, Viganò. [Effect of raubasine and pipratecol on platelet aggregation and on the platelet release reaction]. Clin Ter. 1980 Feb 29;92(4):359-68. Italian. PubMed PMID: 6108818.

2: Passero S, Battistini N. Effect of a Raubasine-Pipratecol association (Isosarpan) on the sympathetic control of cerebral circulation. Acta Neurol (Napoli). 1979 Feb;1(1):45-58. PubMed PMID: 433680.

3: Laubie M, Le Douarec JC. [Pharmacological study of pipratecol (JP 711) and of a pharmaceutical combination raubasine-JP 711]. Arzneimittelforschung. 1969 Nov;19(11):1820-6. French. PubMed PMID: 4391788.

4: Beil W, Staar U, Sewing KF. Substituted thieno[3,4-d]imidazoles, a novel group of H+/K(+)-ATPase inhibitors. Differentiation of their inhibition characteristics from those of omeprazole. Eur J Pharmacol. 1990 Oct 23;187(3):455-67. PubMed PMID: 1963594.