10-Formylfolic acid

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 597165

CAS#: 134-05-4

Description: 10-Formylfolic acid is a potent inhibitor of dihydrofolate reductase.

Chemical Structure

10-Formylfolic acid
CAS# 134-05-4

Theoretical Analysis

MedKoo Cat#: 597165
Name: 10-Formylfolic acid
CAS#: 134-05-4
Chemical Formula: C20H19N7O7
Exact Mass: 469.1346
Molecular Weight: 469.41
Elemental Analysis: C, 51.17; H, 4.08; N, 20.89; O, 23.86

Price and Availability

Size Price Availability Quantity
25.0mg USD 1350.0 2 Weeks
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Synonym: 10-Formylfolic acid;

IUPAC/Chemical Name: (4-(N-((2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl)formamido)benzoyl)-L-glutamic acid


InChi Code: InChI=1S/C20H19N7O7/c21-20-25-16-15(18(32)26-20)23-11(7-22-16)8-27(9-28)12-3-1-10(2-4-12)17(31)24-13(19(33)34)5-6-14(29)30/h1-4,7,9,13H,5-6,8H2,(H,24,31)(H,29,30)(H,33,34)(H3,21,22,25,26,32)/t13-/m0/s1

SMILES Code: O=C(O)CC[C@@H](C(O)=O)NC(C1=CC=C(N(CC2=CN=C3NC(N)=NC(C3=N2)=O)C=O)C=C1)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

Preparing Stock Solutions

The following data is based on the product molecular weight 469.41 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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