L 702007

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MedKoo CAT#: 596673

CAS#: 139547-89-0

Description: L 702007 is a HIV-1 reverse transcriptase inhibitor.


Price and Availability

Size Price Shipping out time Quantity
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Pricing updated 2020-04-01. Prices are subject to change without notice.

L 702007 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 596673
Name: L 702007
CAS#: 139547-89-0
Chemical Formula: C18H25N3O2
Exact Mass: 315.1947
Molecular Weight: 315.41
Elemental Analysis: C, 68.54; H, 7.99; N, 13.32; O, 10.14


Synonym: L 702007; L-702007; L702007; 5-Emmpo;

IUPAC/Chemical Name: 5-ethyl-3-(((5-ethyl-2-methoxy-6-methylpyridin-3-yl)methyl)amino)-6-methylpyridin-2(1H)-one

InChi Key: IUKVADMYSQZSIH-UHFFFAOYSA-N

InChi Code: InChI=1S/C18H25N3O2/c1-6-13-8-15(18(23-5)21-12(13)4)10-19-16-9-14(7-2)11(3)20-17(16)22/h8-9,19H,6-7,10H2,1-5H3,(H,20,22)

SMILES Code: O=C1C(NCC2=CC(CC)=C(C)N=C2OC)=CC(CC)=C(C)N1


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001


References

1: Woolf EJ, Matuszewski B. Simultaneous determination of L-702,007, a HIV-1 reverse transcriptase inhibitor, and its 6-hydroxy metabolite in human plasma by column-switching high-performance liquid chromatography with fluorescence detection. J Chromatogr A. 1996 Apr 5;729(1-2):211-7. PubMed PMID: 9004942.

2: Wai JS, Williams TM, Bamberger DL, Fisher TE, Hoffman JM, Hudcosky RJ, MacTough SC, Rooney CS, Saari WS, Thomas CM, et al. Synthesis and evaluation of 2-pyridinone derivatives as specific HIV-1 reverse transcriptase inhibitors. 3. Pyridyl and phenyl analogs of 3-aminopyridin-2(1H)-one. J Med Chem. 1993 Jan 22;36(2):249-55. PubMed PMID: 7678654.