1,4-DPCA
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 562547

CAS#: 331830-20-7

Description: 1,4-DPCA is a potent and selective inhibitor of prolyl 4-hydroxylase.


Price and Availability

Size
Price

5mg
USD 190
Size
Price

10mg
USD 320
Size
Price

25mg
USD 610

1,4-DPCA, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 562547
Name: 1,4-DPCA
CAS#: 331830-20-7
Chemical Formula: C13H8N2O3
Exact Mass: 240.0535
Molecular Weight: 240.218
Elemental Analysis: C, 65.00; H, 3.36; N, 11.66; O, 19.98


Synonym: 1,4-DPCA; 1,4 DPCA; 1,4DPCA;

IUPAC/Chemical Name: 4-oxo-1,4-dihydro-1,10-phenanthroline-3-carboxylic acid

InChi Key: XZZHOJONZJQARN-UHFFFAOYSA-N

InChi Code: InChI=1S/C13H8N2O3/c16-12-8-4-3-7-2-1-5-14-10(7)11(8)15-6-9(12)13(17)18/h1-6H,(H,15,16)(H,17,18)

SMILES Code: O=C(C(C(O)=O)=CN1)C2=C1C3=C(C=C2)C=CC=N3


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Zhang Y, Strehin I, Bedelbaeva K, Gourevitch D, Clark L, Leferovich J, Messersmith PB, Heber-Katz E. Drug-induced regeneration in adult mice. Sci Transl Med. 2015 Jun 3;7(290):290ra92. doi: 10.1126/scitranslmed.3010228. PubMed PMID: 26041709; PubMed Central PMCID: PMC4687906.

2: Xiong G, Deng L, Zhu J, Rychahou PG, Xu R. Prolyl-4-hydroxylase α subunit 2 promotes breast cancer progression and metastasis by regulating collagen deposition. BMC Cancer. 2014 Jan 2;14:1. doi: 10.1186/1471-2407-14-1. PubMed PMID: 24383403; PubMed Central PMCID: PMC3880410.

3: Love RJ, Jones KS. Transient inhibition of connective tissue infiltration and collagen deposition into porous poly(lactic-co-glycolic acid) discs. J Biomed Mater Res A. 2013 Dec;101(12):3599-606. doi: 10.1002/jbm.a.34648. Epub 2013 Jun 14. PubMed PMID: 23766241.