WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 562547

CAS#: 331830-20-7

Description: 1,4-DPCA is a potent and selective inhibitor of prolyl 4-hydroxylase.

Chemical Structure

CAS# 331830-20-7

Theoretical Analysis

MedKoo Cat#: 562547
Name: 1,4-DPCA
CAS#: 331830-20-7
Chemical Formula: C13H8N2O3
Exact Mass: 240.0535
Molecular Weight: 240.218
Elemental Analysis: C, 65.00; H, 3.36; N, 11.66; O, 19.98

Price and Availability

Size Price Availability Quantity
5.0mg USD 190.0 2 Weeks
10.0mg USD 320.0 2 Weeks
25.0mg USD 610.0 2 Weeks
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Synonym: 1,4-DPCA; 1,4 DPCA; 1,4DPCA;

IUPAC/Chemical Name: 4-oxo-1,4-dihydro-1,10-phenanthroline-3-carboxylic acid


InChi Code: InChI=1S/C13H8N2O3/c16-12-8-4-3-7-2-1-5-14-10(7)11(8)15-6-9(12)13(17)18/h1-6H,(H,15,16)(H,17,18)

SMILES Code: O=C(C(C(O)=O)=CN1)C2=C1C3=C(C=C2)C=CC=N3

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Certificate of Analysis:

Safety Data Sheet (SDS):

Preparing Stock Solutions

The following data is based on the product molecular weight 240.218 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Zhang Y, Strehin I, Bedelbaeva K, Gourevitch D, Clark L, Leferovich J, Messersmith PB, Heber-Katz E. Drug-induced regeneration in adult mice. Sci Transl Med. 2015 Jun 3;7(290):290ra92. doi: 10.1126/scitranslmed.3010228. PubMed PMID: 26041709; PubMed Central PMCID: PMC4687906.

2: Xiong G, Deng L, Zhu J, Rychahou PG, Xu R. Prolyl-4-hydroxylase α subunit 2 promotes breast cancer progression and metastasis by regulating collagen deposition. BMC Cancer. 2014 Jan 2;14:1. doi: 10.1186/1471-2407-14-1. PubMed PMID: 24383403; PubMed Central PMCID: PMC3880410.

3: Love RJ, Jones KS. Transient inhibition of connective tissue infiltration and collagen deposition into porous poly(lactic-co-glycolic acid) discs. J Biomed Mater Res A. 2013 Dec;101(12):3599-606. doi: 10.1002/jbm.a.34648. Epub 2013 Jun 14. PubMed PMID: 23766241.