Ginsenoside Rb1 | CAS#41753-43-9

Ginsenoside Rb1
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WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 315132

CAS#: 41753-43-9

Description: Ginsenoside Rb1: appears to be most abundant in Panax quinquefolius (American Ginseng). Ginsenoside Rb1 seems to affect the reproductive system in animal testicles. Recent research shows that Ginsenoside Rb1 affects rat embryo development and has teratogenic effects, causing birth defects. Another study shows that Ginsenoside Rb1 may increase testosterone production in male rats indirectly through the stimulation of the luteinizing hormone. Traditional Chinese medicine asserts that Panax quinquefolius promotes yin in the body. Ginsenoside Rb1 also inhibits chemoinvasion and angiogenesis. (Source: http://en.wikipedia.org/wiki/Ginsenoside )

Chemical Structure

Ginsenoside Rb1

CAS# 41753-43-9

Instruction

Theoretical Analysis

MedKoo Cat#: 315132
Name: Ginsenoside Rb1
CAS#: 41753-43-9
Chemical Formula: C54H92O23
Exact Mass: 1,108.60
Molecular Weight: 1,109.290
Elemental Analysis: C, 58.47; H, 8.36; O, 33.17

Price and Availability

Size	Price	Availability	Quantity
10mg	USD 670
Bulk inquiry Welcome, Customer: Please do not inquire quote if your intended use is for a patient since our products are for research use and for chemical synthesis use, not for human use . For in-stock products, we listed price in the web page. You may inquire prices for which sizes were not listed. If no price is listed, this means the product is not in stock at the moment, which may be available via custom synthesis. For cost-effective reason, minimum order of 1g is requested (typically very expensive). The lead time is usually 2-4 months. Quote of less than 1g will not be provided. MedKoo may not offer quote for below reasons: (1) current available synthetic method appears to be extremely expensive which is obviously not affordable to most customers; (2) Key raw material to make the product is temporally not available; (3) DEA controlled substances; (4) the product is under patent protection in customer’s country.

Synonym: (3beta12beta)20(6ObetaDGlucopyranosylbetaDglucopyranosyl)oxy12hydroxydammar24en3yl2ObetaDglucopyranosylbetaDglucopyranoside

IUPAC/Chemical Name: (2S,3R,4S,5S,6R)-2-(((2R,3R,4S,5S,6R)-4,5-dihydroxy-2-(((8R,10R,12S,13S,14S,17S)-12-hydroxy-4,4,8,10,14-pentamethyl-17-((S)-6-methyl-2-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-((((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl)oxy)hept-5-en-2-yl)hexadecahydro-1H-cyclopenta[a]phenanthren-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol

InChi Key: GZYPWOGIYAIIPV-MCAKJACCSA-N

InChi Code: InChI=1S/C54H92O23/c1-23(2)10-9-14-54(8,77-48-44(69)40(65)37(62)29(74-48)22-70-46-42(67)38(63)34(59)26(19-55)71-46)24-11-16-53(7)33(24)25(58)18-31-51(5)15-13-32(50(3,4)30(51)12-17-52(31,53)6)75-49-45(41(66)36(61)28(21-57)73-49)76-47-43(68)39(64)35(60)27(20-56)72-47/h10,24-49,55-69H,9,11-22H2,1-8H3/t24-,25-,26+,27+,28+,29+,30?,31?,32?,33+,34+,35+,36+,37+,38-,39-,40-,41-,42+,43+,44+,45+,46+,47-,48-,49-,51-,52+,53-,54-/m0/s1

SMILES Code: O[C@H]1[C@H](O[C@H]2[C@H](OC3CC[C@]4(C)C5C[C@H](O)[C@@]6([H])[C@@H]([C@](CC/C=C(C)\C)(O[C@H]7[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO[C@H]8[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O8)O7)C)CC[C@]6(C)[C@]5(C)CCC4C3(C)C)O[C@H](CO)[C@@H](O)[C@@H]2O)O[C@H](CO)[C@@H](O)[C@@H]1O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO.

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Instruction:

View handling instruction

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 1,109.29 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Shen L, Haas M, Wang DQ, May A, Lo CC, Obici S, Tso P, Woods SC, Liu M.
Ginsenoside Rb1 increases insulin sensitivity by activating AMP-activated protein
kinase in male rats. Physiol Rep. 2015 Sep;3(9). pii: e12543. doi:
10.14814/phy2.12543. PubMed PMID: 26359241.

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Ginsenoside Rb1 featured