UCL-TRO-1938
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 125783

CAS#: 2919575-27-0

Description: UCL-TRO-1938 is a potent allosteric activator of PI3Kα with an EC50 value of approximately 60 μM.

Chemical Structure

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UCL-TRO-1938
CAS# 2919575-27-0
Instruction

Theoretical Analysis

MedKoo Cat#: 125783
Name: UCL-TRO-1938
CAS#: 2919575-27-0
Chemical Formula: C27H32N6O
Exact Mass: 456.26
Molecular Weight: 456.590
Elemental Analysis: C, 71.03; H, 7.06; N, 18.41; O, 3.50

Price and Availability

Size Price Availability Quantity
5mg USD 650 2 Weeks
25mg USD 1350 2 Weeks
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Synonym: UCL-TRO-1938; EX-A7977; HY-154848; CS-0834806

IUPAC/Chemical Name: 1-(7-((2-((4-(4-ethylpiperazin-1-yl)phenyl)amino)pyridin-4-yl)amino)indolin-1-yl)ethan-1-one

InChi Key: RPOHONUDGBSZDK-UHFFFAOYSA-N

InChi Code: InChI=1S/C27H32N6O/c1-3-31-15-17-32(18-16-31)24-9-7-22(8-10-24)30-26-19-23(11-13-28-26)29-25-6-4-5-21-12-14-33(20(2)34)27(21)25/h4-11,13,19H,3,12,14-18H2,1-2H3,(H2,28,29,30)

SMILES Code: CCN1CCN(CC1)C2=CC=C(C=C2)NC3=NC=CC(=C3)NC4=CC=CC5=C4N(CC5)C(=O)C

Appearance: To be determined

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 456.59 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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