Cytidine triphosphate

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 125445

CAS#: 65-47-4

Description: CTP is a pyrimidine ribonucleoside 5'-triphosphate and a cytidine 5'-phosphate. It has a role as an Escherichia coli metabolite and a mouse metabolite.

Chemical Structure

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Cytidine triphosphate
CAS# 65-47-4
Instruction

Theoretical Analysis

MedKoo Cat#: 125445
Name: Cytidine triphosphate
CAS#: 65-47-4
Chemical Formula: C9H16N3O14P3
Exact Mass: 482.98
Molecular Weight: 483.160
Elemental Analysis: C, 22.37; H, 3.34; N, 8.70; O, 46.36; P, 19.23

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Cytidine triphosphate; cytidine-5'-triphosphate; 65-47-4; Cytidine 5'-(tetrahydrogen triphosphate); Cytidine 5'-triphosphate

IUPAC/Chemical Name: ((2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate

InChi Key: PCDQPRRSZKQHHS-XVFCMESISA-N

InChi Code: InChI=1S/C9H16N3O14P3/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H2,10,11,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1

SMILES Code: NC1=NC(=O)N(C=C1)[C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O

Appearance: To be determined

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 483.16 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Zhu M, Sun W, Wang Y, Meng J, Zhang D, Guo T, Ouyang P, Ying H, Xie J.
Engineered cytidine triphosphate synthetase with reduced product inhibition.
Protein Eng Des Sel. 2014 Jul;27(7):225-33. doi: 10.1093/protein/gzu019. Epub
2014 Jun 5. PMID: 24902851.

2: Jalal AS, Tran NT, Le TB. ParB spreading on DNA requires cytidine
triphosphate in vitro. Elife. 2020 Feb 20;9:e53515. doi: 10.7554/eLife.53515.
PMID: 32077854; PMCID: PMC7053999.

3: Long C, Koshland DE Jr. Cytidine triphosphate synthetase. Methods Enzymol.
1978;51:79-83. doi: 10.1016/s0076-6879(78)51014-8. PMID: 357909.

4: van den Berg AA, van Lenthe H, Kipp JB, de Korte D, van Kuilenburg AB, van
Gennip AH. Cytidine triphosphate (CTP) synthetase activity during cell cycle
progression in normal and malignant T-lymphocytic cells. Eur J Cancer.
1995;31A(1):108-12. doi: 10.1016/0959-8049(94)00442-8. PMID: 7695960.