FLC26

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 122715

CAS#: 1225291-21-3

Description: FLC26 is a CK2 inhibitor with IC50 = 9 nM


Chemical Structure

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FLC26
CAS# 1225291-21-3

Theoretical Analysis

MedKoo Cat#: 122715
Name: FLC26
CAS#: 1225291-21-3
Chemical Formula: C16H8Br2O5
Exact Mass: 437.87
Molecular Weight: 440.040
Elemental Analysis: C, 43.67; H, 1.83; Br, 36.32; O, 18.18

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: FLC26; FLC 26; FLC-26

IUPAC/Chemical Name: 4-(6,8-dibromo-3-hydroxy-4-oxo-4H-chromen-2-yl)benzoic acid

InChi Key: GDOSILZXICLCEI-UHFFFAOYSA-N

InChi Code: InChI=1S/C16H8Br2O5/c17-9-5-10-12(19)13(20)14(23-15(10)11(18)6-9)7-1-3-8(4-2-7)16(21)22/h1-6,20H,(H,21,22)

SMILES Code: OC(C(C=C1)=CC=C1C2=C(O)C(C3=CC(Br)=CC(Br)=C3O2)=O)=O

Appearance: To be determined

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 440.04 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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Guerra B, Bischoff N, Bdzhola VG, Yarmoluk SM, Issinger OG, Golub AG, Niefind K. A Note of Caution on the Role of Halogen Bonds for Protein Kinase/Inhibitor Recognition Suggested by High- And Low-Salt CK2α Complex Structures. ACS Chem Biol. 2015 Jul 17;10(7):1654-60. doi: 10.1021/acschembio.5b00235. Epub 2015 May 15. PMID: 25961323.