D-Amino-PEG6-Thalidomide TFA salt
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MedKoo CAT#: 122043

CAS#: N/A

Description: D-Amino-PEG6-Thalidomide TFA salt is comprised of an amine group linked to ?-Phthalimidoglutarimide through PEG6. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Thalidomide group is useful in PROTAC research and often referred to as dBET1 as a powerful BRD4 degrader.

Chemical Structure

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D-Amino-PEG6-Thalidomide TFA salt
CAS# N/A
Instruction

Theoretical Analysis

MedKoo Cat#: 122043
Name: D-Amino-PEG6-Thalidomide TFA salt
CAS#: N/A
Chemical Formula: C27H39N3O10
Exact Mass: 565.26
Molecular Weight: 565.620
Elemental Analysis: C, 57.33; H, 6.95; N, 7.43; O, 28.29

Price and Availability

Size Price Availability Quantity
50mg USD 1050 2 Weeks
100mg USD 1650 2 Weeks
250mg USD 3050 2 Weeks
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Synonym: D-Amino-PEG6-Thalidomide TFA salt

IUPAC/Chemical Name: 2-(1-(20-amino-3,6,9,12,15,18-hexaoxaicosyl)-2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione

InChi Key: SBCVQPNTHBDMCS-UHFFFAOYSA-N

InChi Code: InChI=1S/C27H39N3O10/c28-7-9-35-11-13-37-15-17-39-19-20-40-18-16-38-14-12-36-10-8-29-24(31)6-5-23(27(29)34)30-25(32)21-3-1-2-4-22(21)26(30)33/h1-4,23H,5-20,28H2

SMILES Code: O=C1N(C2C(N(CCOCCOCCOCCOCCOCCOCCN)C(CC2)=O)=O)C(C3=CC=CC=C31)=O

Appearance: To be determined

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 565.62 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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