ZYH

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 208398

CAS#: unknown

Description: ZYH is a monoacylglycerol lipase (MAGL) inhibitor

Chemical Structure

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ZYH
CAS# unknown
Instruction

Theoretical Analysis

MedKoo Cat#: 208398
Name: ZYH
CAS#: unknown
Chemical Formula: C25H30N6O2
Exact Mass: 446.24
Molecular Weight: 446.560
Elemental Analysis: C, 67.24; H, 6.77; N, 18.82; O, 7.17

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym:

IUPAC/Chemical Name: (2-Cyclohexyl-1,3-benzoxazol-6-yl)-[3-(4-pyrimidin-2-ylpiperazin-1-yl)azetidin-1-yl]methanone

InChi Key: IABLYMUVWHQTGC-UHFFFAOYSA-N

InChi Code: InChI=1S/C25H30N6O2/c32-24(19-7-8-21-22(15-19)33-23(28-21)18-5-2-1-3-6-18)31-16-20(17-31)29-11-13-30(14-12-29)25-26-9-4-10-27-25/h4,7-10,15,18,20H,1-3,5-6,11-14,16-17H2

SMILES Code: O=C(C1=CC=C2N=C(C3CCCCC3)OC2=C1)N4CC(N5CCN(C6=NC=CC=N6)CC5)C4

Appearance: To be determined

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 446.56 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Dhar P, Vinu R. Microwave-Assisted Catalytic Solvolysis of Lignin to Phenols: Kinetics and Product Characterization. ACS Omega. 2018 Nov 8;3(11):15076-15085. doi: 10.1021/acsomega.8b01509. PMID: 31458173; PMCID: PMC6643774.


2: Jia P, Xia H, Tang K, Zhou Y. Plasticizers Derived from Biomass Resources: A Short Review. Polymers (Basel). 2018 Nov 24;10(12):1303. doi: 10.3390/polym10121303. PMID: 30961228; PMCID: PMC6401779.


3: Tang W, Zhao Y, Wang C, Shan B, Cui J. Heavy metal contamination of overlying waters and bed sediments of Haihe Basin in China. Ecotoxicol Environ Saf. 2013 Dec;98:317-23. doi: 10.1016/j.ecoenv.2013.09.038. Epub 2013 Oct 18. PMID: 24144997.


4: Yu H, Chen F, Li X, Huang H, Zhang Q, Su S, Wang K, Mao E, Mei B, Mul G, Ma T, Zhang Y. Synergy of ferroelectric polarization and oxygen vacancy to promote CO2 photoreduction. Nat Commun. 2021 Jul 28;12(1):4594. doi: 10.1038/s41467-021-24882-3. PMID: 34321482; PMCID: PMC8319429.


5: Brooks NA, Narayan V, Hegarty PK, Zafirakis H, Han XY, Kamat AM. The role of the urologist, BCG vaccine administration, and SARS-CoV-2: An overview. BJUI Compass. 2020 Jul;1(3):87-92. doi: 10.1002/bco2.21. Epub 2020 Jun 22. PMID: 32835353; PMCID: PMC7361196.


6: Chen C, Yihe Z, Wanjia H, Cheng Q, Yongfan L, Na Z. Incorporation of Xuan- paper waste residue in red mud/waste polyethylene composites. J Hazard Mater. 2020 Nov 15;399:123051. doi: 10.1016/j.jhazmat.2020.123051. Epub 2020 May 27. PMID: 32937712.


7: Zhang Y, Ma Z, Zhang Y, Li B, Feng M, Zhao Y, An Q. Biofriendly molecular and protein release substrate with integrated piezoelectric motivation and anti- oxidative stress capabilities. Nanoscale. 2021 May 13;13(18):8481-8489. doi: 10.1039/d1nr01676h. PMID: 33908572.


8: Wei Y, Wu P, Zhu Z, Liu L, Liu C, Hu J, Wang S, Zhang Y. Surface-Plasmon- Resonance-Based Optical-Fiber Micro-Displacement Sensor with Temperature Compensation. Sensors (Basel). 2018 Sep 23;18(10):3210. doi: 10.3390/s18103210. PMID: 30249035; PMCID: PMC6210995.


9: Zhao Y, Zhong Y, Ye C, Liang P, Pan X, Zhang YY, Zhang Y, Shen Y. Multi-omics analyses on Kandelia obovata reveal its response to transplanting and genetic differentiation among populations. BMC Plant Biol. 2021 Jul 19;21(1):341. doi: 10.1186/s12870-021-03123-1. PMID: 34281510; PMCID: PMC8287808.


10: Pei J, Yu X, Wei S, Boukherroub R, Zhang Y. Double-side effect of B/C ratio on BDD electrode detection for heavy metal ion in water. Sci Total Environ. 2021 Jun 1;771:145430. doi: 10.1016/j.scitotenv.2021.145430. Epub 2021 Jan 28. PMID: 33736132