RBN013209
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 121009

CAS#: 2597933-17-8

Description: RBN013209 is a potent and selective small molecule inhibitor of CD38 catalytic function. RBN013209 inhibits intracellular CD38 activity and elevates intracellular NAD+ levels in cultured human primary T cells.

Chemical Structure

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RBN013209
CAS# 2597933-17-8
Instruction

Theoretical Analysis

MedKoo Cat#: 121009
Name: RBN013209
CAS#: 2597933-17-8
Chemical Formula: C19H24N6O3
Exact Mass: 384.19
Molecular Weight: 384.440
Elemental Analysis: C, 59.36; H, 6.29; N, 21.86; O, 12.48

Price and Availability

Size Price Availability Quantity
5mg USD 950 2 Weeks
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Synonym: RBN013209; RBN 013209; RBN-013209

IUPAC/Chemical Name: 2-(1H-imidazol-1-yl)-N-((1r,4r)-4-(2-methoxyethoxy)cyclohexyl)-5H-pyrrolo[3,2-d]pyrimidine-4-carboxamide

InChi Key: VQRPLBOIYMUPNF-HDJSIYSDSA-N

InChi Code: InChI=1S/C19H24N6O3/c1-27-10-11-28-14-4-2-13(3-5-14)22-18(26)17-16-15(6-7-21-16)23-19(24-17)25-9-8-20-12-25/h6-9,12-14,21H,2-5,10-11H2,1H3,(H,22,26)/t13-,14-

SMILES Code: O=C(N[C@@H]1CC[C@@H](OCCOC)CC1)C2=NC(N3C=CN=C3)=NC4=C2NC=C4

Appearance: To be determined

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 384.44 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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Prashant Shambharkar, Danielle J. Blackwell, Melissa M. Vasbinder, Laurie B. Schenkel, Kaiko Kunii, Jenkins L. Lemera, Kristy G. Kuplast-Barr, Yue Ren, Ellen Bamberg, W. David Church, Christina R. Majer, Luke Utley, Kristen McEachern, Mario Niepel, Tim J. Wigle, Kevin W. Kuntz, Victoria M. Richon, Heike Keilhack, Joseph M. Gozgit; Abstract 1344: Small molecule inhibitor of CD38 modulates its intra- and extracellular functions leading to antitumor activity. Cancer Res 1 July 2021; 81 (13_Supplement): 1344.