Androsin
featured

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 112191

CAS#: 531-28-2

Description: Androsin inhibits bronchial obstruction in a guinea pig model of asthma induced by ovalbumin or platelet-activating factor (PAF).


Chemical Structure

img
Androsin
CAS# 531-28-2

Theoretical Analysis

MedKoo Cat#: 112191
Name: Androsin
CAS#: 531-28-2
Chemical Formula: C15H20O8
Exact Mass: 328.12
Molecular Weight: 328.320
Elemental Analysis: C, 54.88; H, 6.14; O, 38.98

Price and Availability

Size Price Availability Quantity
1mg USD 270 2 Weeks
5mg USD 660 2 Weeks
10mg USD 1050 2 Weeks
25mg USD 1580 2 Weeks
Bulk inquiry

Synonym: Androsin

IUPAC/Chemical Name: 1-(3-methoxy-4-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)phenyl)ethan-1-one

InChi Key: QUOZWMJFTQUXON-UXXRCYHCSA-N

InChi Code: InChI=1S/C15H20O8/c1-7(17)8-3-4-9(10(5-8)21-2)22-15-14(20)13(19)12(18)11(6-16)23-15/h3-5,11-16,18-20H,6H2,1-2H3/t11-,12-,13+,14-,15-/m1/s1

SMILES Code: COC1=C(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)C=CC(C(C)=O)=C1

Appearance: To be determined

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 328.32 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

1: Dorsch W, Stuppner H, Wagner H, Gropp M, Demoulin S, Ring J. Antiasthmatic effects of Picrorhiza kurroa: androsin prevents allergen- and PAF-induced bronchial obstruction in guinea pigs. Int Arch Allergy Appl Immunol. 1991;95(2-3):128-33. doi: 10.1159/000235416. PMID: 1718906.


2: Stuppner H, Wagner H. Minor Iridoid and Phenol Glycosides of Picrorhiza kurrooa. Planta Med. 1989 Oct;55(5):467-9. doi: 10.1055/s-2006-962066. PMID: 17262460.


3: Kim JS, Shim SH, Xu YN, Kang SS, Son KH, Chang HW, Kim HP, Bae K. Phenolic glycosides from Pyrola japonica. Chem Pharm Bull (Tokyo). 2004 Jun;52(6):714-7. doi: 10.1248/cpb.52.714. PMID: 15187393.


4: Wang H, Sun Y, Ye WC, Xiong F, Wu JJ, Yang CH, Zhao SX. Antioxidative phenylethanoid and phenolic glycosides from Picrorhiza scrophulariiflora. Chem Pharm Bull (Tokyo). 2004 May;52(5):615-7. doi: 10.1248/cpb.52.615. PMID: 15133218.


5: Sakamoto Y, Inoue N, Nakanishi Y, Ninomiya K, Yoshikawa M, Muraoka O, Manse Y, Morikawa T. Hepatoprotective Principles from the Rhizomes of Picrorhiza kurroa. Biol Pharm Bull. 2023;46(6):848-855. doi: 10.1248/bpb.b23-00167. PMID: 37258151.


6: Chen Z, Wu J, Shen W, Liu P, Cao Y, Lu Y. Counter-current chromatographic method for preparative scale isolation of picrosides from traditional Chinese medicine Picrorhiza scrophulariiflora. J Sep Sci. 2011 Aug;34(15):1910-6. doi: 10.1002/jssc.201100025. Epub 2011 Jul 1. PMID: 21721121.


7: De Rosa S, De Giulio A, Tommonaro G. Aliphatic and aromatic glycosides from the cell cultures of Lycopersicon esculentum. Phytochemistry. 1996 Jul;42(4):1031-4. doi: 10.1016/0031-9422(96)00083-0. PMID: 8688181.


8: Dorsch W, Wagner H, Neszmelyi A, Stuppner H. Acetophenones: Highly Active Antiasthmatic Compounds of Plant Origin. Int Arch Allergy Immunol. 1992;99(2-4):493-495. doi: 10.1159/000236322. Epub 2009 Sep 2. PMID: 34167259.


9: Dorsch W, Müller A, Christoffel V, Stuppner H, Antus S, Gottsegen A, Wagner H. Antiasthmatic acetophenones - an in vivo study on structure activity relationship. Phytomedicine. 1994 Jun;1(1):47-54. doi: 10.1016/S0944-7113(11)80022-X. PMID: 23195815.


10: Kim IH, Kaneko N, Uchiyama N, Lee JE, Takeya K, Kawahara N, Goda Y. Two phenylpropanoid glycosides from Neopicrorhiza scrophulariiflora. Chem Pharm Bull (Tokyo). 2006 Feb;54(2):275-7. doi: 10.1248/cpb.54.275. PMID: 16462084.


11: Monthakantirat O, De-Eknamkul W, Umehara K, Yoshinaga Y, Miyase T, Warashina T, Noguchi H. Phenolic constituents of the rhizomes of the Thai medicinal plant Belamcanda chinensis with proliferative activity for two breast cancer cell lines. J Nat Prod. 2005 Mar;68(3):361-4. doi: 10.1021/np040175c. PMID: 15787436.


12: Dorsch W, Wagner H. New antiasthmatic drugs from traditional medicine? Int Arch Allergy Appl Immunol. 1991;94(1-4):262-5. doi: 10.1159/000235378. PMID: 1937886.


13: Nan ZD, Zhao MB, Jiang Y, Tu PF. [Chemical constituents from stems of Cistanche deserticola cultured in Tarim desert]. Zhongguo Zhong Yao Za Zhi. 2013 Aug;38(16):2665-70. Chinese. PMID: 24228584.


14: Amin HIM, Hussain FHS, Najmaldin SK, Thu ZM, Ibrahim MF, Gilardoni G, Vidari G. Phytochemistry and Biological Activities of Iris Species Growing in Iraqi Kurdistan and Phenolic Constituents of the Traditional Plant Iris postii. Molecules. 2021 Jan 7;26(2):264. doi: 10.3390/molecules26020264. PMID: 33430398; PMCID: PMC7827031.


15: Gingell JC, Knönagel H, Kurth KH, Tunn UW. Placebo controlled double-blind study to test the efficacy of the aromatase inhibitor atamestane in patients with benign prostatic hyperplasia not requiring operation. The Schering 90.062 Study Group. J Urol. 1995 Aug;154(2 Pt 1):399-401. doi: 10.1097/00005392-199508000-00020. PMID: 7541854.


16: Xie GY, Chen YJ, Wen R, Xu JY, Wu SS, Qin MJ. [Chemical constituents from rhizomes of Iris germanica]. Zhongguo Zhong Yao Za Zhi. 2014 Mar;39(5):846-50. Chinese. PMID: 25204177.


17: Wu C, Wang Y, Sun H. Targeted and untargeted metabolomics reveals deep analysis of drought stress responses in needles and roots of Pinus taeda seedlings. Front Plant Sci. 2023 Jan 31;13:1031466. doi: 10.3389/fpls.2022.1031466. PMID: 36798806; PMCID: PMC9927248.


18: Xu X, Wei T, Xue Q, Ai J, Li G, Liu Z, Li D, Hou J, Jin H, Liu Y, Liang X. [Analysis on quality value transmitting of Qinggusan reference sample of classical prescription based on quantitative fingerprint technology]. Se Pu. 2023 Feb;41(2):142-151. Chinese. doi: 10.3724/SP.J.1123.2022.09024. PMID: 36725710; PMCID: PMC9892975.