Metamizil hydrochloride

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 577209

CAS#: 10503-18-1

Description: Metamizil hydrochloride is a cholinolytic agent -- an agent that blocks the transmission of excitation from cholinergic nerve fibers -- and an antagonist of the mediator acetylcholine.

Chemical Structure

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Metamizil hydrochloride
CAS# 10503-18-1
Instruction

Theoretical Analysis

MedKoo Cat#: 577209
Name: Metamizil hydrochloride
CAS#: 10503-18-1
Chemical Formula: C21H28ClNO3
Exact Mass: 377.18
Molecular Weight: 377.910
Elemental Analysis: C, 66.74; H, 7.47; Cl, 9.38; N, 3.71; O, 12.70

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: Metamizil hydrochloride; Metamizil HCl

IUPAC/Chemical Name: Benzeneacetic acid, alpha-hydroxy-alpha-phenyl-, 2-(diethylamino)-1-methylethyl ester, hydrochloride

InChi Key: ZYBYLUFJVWSUII-UHFFFAOYSA-N

InChi Code: InChI=1S/C21H27NO3.ClH/c1-4-22(5-2)16-17(3)25-20(23)21(24,18-12-8-6-9-13-18)19-14-10-7-11-15-19;/h6-15,17,24H,4-5,16H2,1-3H3;1H

SMILES Code: Cl.CCN(CC)CC(C)OC(=O)C(O)(c1ccccc1)c2ccccc2

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 377.91 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1. BORODKIN IuS. VLIIANIE AMIZIJA, METAMIZILA I DRUGIKH TSENTRAL'NYKH KHOLINOLITIKOV NA SUDOROZHNY I POROG GIPPOKAMPA I POROG REAKTSII AKTIVATSII [EFFECT OF AMIZIL, METAMIZIL AND OTHER CENTRAL CHOLINOLYTICS ON THE CONVULSIVE THRESHOLD OF THE HIPPOCAMPUS AND ON THE THRESHOLD OF THE ACTIVATION REACTION]. Farmakol Toksikol. 1964 Nov-Dec;27:651-4. Russian. PMID: 14321282.