Nolinium Free Base

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 414456

CAS#: 730233-46-2 (free base)

Description: Nolinium Free Base is an Anti-Ulcerative and Antisecretory


Chemical Structure

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Nolinium Free Base
CAS# 730233-46-2 (free base)

Theoretical Analysis

MedKoo Cat#: 414456
Name: Nolinium Free Base
CAS#: 730233-46-2 (free base)
Chemical Formula: C15H11Cl2N2+
Exact Mass: 289.03
Molecular Weight: 290.170
Elemental Analysis: C, 62.09; H, 3.82; Cl, 24.43; N, 9.65

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Related CAS #: 730233-46-2 (free base); 40759-33-9 (Br)  

Synonym: Nolinium cation; Nolinium Free Base; Diclonium

IUPAC/Chemical Name: 2-((3,4-dichlorophenyl)amino)quinolizin-5-ium

InChi Key: MTFYFZDTISVQRR-UHFFFAOYSA-O

InChi Code: InChI=1S/C15H10Cl2N2/c16-14-5-4-11(10-15(14)17)18-12-6-8-19-7-2-1-3-13(19)9-12/h1-10H/p+1

SMILES Code: Clc1c(Cl)cc(Nc(cc2)cc3[n+]2cccc3)cc1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 290.17 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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5: Goldenberg MM, Moore RB. Effect of nolinium bromide, cimetidine, and oxyphencyclimine on gastric hypersecretion induced by some secretagogues in the rat. Arch Int Pharmacodyn Ther. 1980 Sep;247(1):163-76. PMID: 7004367.

6: Brooks RR, Goldenberg MM. Inhibition of guinea pig gastric microsomal potassium-stimulated ATPase by nolinium bromide. Proc Soc Exp Biol Med. 1983 Mar;172(3):308-15. doi: 10.3181/00379727-172-41562. PMID: 6302706.

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8: Sasaki T, Tadokoro K, Yanagisawa T, Higashi S, Garant PR. H+-K+-ATPase activity in the rat incisor enamel organ during enamel formation. Anat Rec. 1988 Aug;221(4):823-33. doi: 10.1002/ar.1092210406. PMID: 2847591.

9: Spielmann HP, Wemmer DE, Jacobsen JP. Solution structure of a DNA complex with the fluorescent bis-intercalator TOTO determined by NMR spectroscopy. Biochemistry. 1995 Jul 11;34(27):8542-53. doi: 10.1021/bi00027a004. PMID: 7612596.

10: Dousa TP, Hui YS, Northrup TE, Goldenberg MM. Inhibition of histamine- sensitive adenylate cyclase from the guinea pig gastric mucosa by nolinium bromide. Biochem Pharmacol. 1979;28(2):343-4. doi: 10.1016/0006-2952(79)90528-8. PMID: 426848.