Nabam

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 111501

CAS#: 142-59-6

Description: Nabam is the dithiocarbamate salt of ethylenebisdithiocarbamic acid. It is used as a fungicide, algicide, and bactericide on crops, and is also considered to be a carcinogen.

Chemical Structure

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Nabam
CAS# 142-59-6
Instruction

Theoretical Analysis

MedKoo Cat#: 111501
Name: Nabam
CAS#: 142-59-6
Chemical Formula: C4H6N2Na2S4
Exact Mass: 0.00
Molecular Weight: 256.330
Elemental Analysis: C, 18.74; H, 2.36; N, 10.93; Na, 17.94; S, 50.03

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Related CAS #: 142-59-6 (salt); 111-54-6 (free acid)  

Synonym: AI3-04473; AI304473; AI3 04473; Chem BAM; Dithane A-40; Dithane D-14; DSE; ENT 9106; HSDB 1170; HSDB1170; HSDB-1170; NSC 147803; NSC147803; NSC-147803; NSC 49511; NSC49511; NSC-49511; NSC 49511; Parzate; X-Spor;

IUPAC/Chemical Name: sodium ethane-1,2-diyldicarbamodithioate

InChi Key: UQJQVUOTMVCFHX-UHFFFAOYSA-L

InChi Code: InChI=1S/C4H8N2S4.2Na/c7-3(8)5-1-2-6-4(9)10;;/h1-2H2,(H2,5,7,8)(H2,6,9,10);;/q;2*+1/p-2

SMILES Code: S=C([S-])NCCNC([S-])=S.[Na+].[Na+]

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 256.33 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Anderson CC, Marentette JO, Rauniyar AK, Prutton KM, Khatri M, Matheson C, Reisz JA, Reigan P, D'Alessandro A, Roede JR. Maneb alters central carbon metabolism and thiol redox status in a toxicant model of Parkinson's disease. Free Radic Biol Med. 2021 Jan;162:65-76. doi: 10.1016/j.freeradbiomed.2020.11.028. Epub 2020 Dec 3. PMID: 33279619; PMCID: PMC7889696.

2: Hoffman L, Trombetta L, Hardej D. Ethylene bisdithiocarbamate pesticides Maneb and Mancozeb cause metal overload in human colon cells. Environ Toxicol Pharmacol. 2016 Jan;41:78-88. doi: 10.1016/j.etap.2015.11.002. Epub 2015 Nov 7. PMID: 26650801.

3: Schmidt B, Christensen HB, Petersen A, Sloth JJ, Poulsen ME. Method validation and analysis of nine dithiocarbamates in fruits and vegetables by LC- MS/MS. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2013;30(7):1287-98. doi: 10.1080/19440049.2013.801083. Epub 2013 Jun 25. PMID: 23799268.

4: Koch P. Occupational allergic contact dermatitis and airborne contact dermatitis from 5 fungicides in a vineyard worker. Cross-reactions between fungicides of the dithiocarbamate group? Contact Dermatitis. 1996 May;34(5):324-9. doi: 10.1111/j.1600-0536.1996.tb02216.x. PMID: 8807224.

5: Miles CJ, Zhou M. Determination of nabam fungicide in crops by liquid chromatography with postcolumn reaction detection. J Assoc Off Anal Chem. 1991 Mar-Apr;74(2):384-8. PMID: 1904852.

6: Vettorazzi G, Almeida WF, Burin GJ, Jaeger RB, Puga FR, Rahde AF, Reyes FG, Schvartsman S. International safety assessment of pesticides: dithiocarbamate pesticides, ETU, and PTU--a review and update. Teratog Carcinog Mutagen. 1995-1996;15(6):313-37. doi: 10.1002/(SICI)1520-6866(1996)15:6<313::AID- TCM7>3.0.CO;2-L. PMID: 8732882.