Indorenate

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 576686

CAS#: 73758-06-2

Description: Indorenate is a biochemical with antihypertensive, anorectic, stimulus control and anxiolytic-like activity.

Chemical Structure

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Indorenate
CAS# 73758-06-2
Instruction

Theoretical Analysis

MedKoo Cat#: 576686
Name: Indorenate
CAS#: 73758-06-2
Chemical Formula: C13H16N2O3
Exact Mass: 248.12
Molecular Weight: 248.280
Elemental Analysis: C, 62.89; H, 6.50; N, 11.28; O, 19.33

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: Indorenate

IUPAC/Chemical Name: Methyl (+-)-alpha-(aminomethyl)-5-methoxyindol-3-acetate

InChi Key: YFEDJMLMWJSRJJ-UHFFFAOYSA-N

InChi Code: InChI=1S/C13H16N2O3/c1-17-8-3-4-12-9(5-8)11(7-15-12)10(6-14)13(16)18-2/h3-5,7,10,15H,6,14H2,1-2H3

SMILES Code: COC(=O)C(CN)c1c[nH]c2ccc(OC)cc12

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 248.28 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1. Bravo G, Ibarra A, Guizar-Sahagún G, Rojas G, Hong E. Indorenate improves motor function in rats with chronic spinal cord injury. Basic Clin Pharmacol Toxicol. 2007 Jan;100(1):67-70. doi: 10.1111/j.1742-7843.2007.00004.x. PMID: 17214613.

2. Martínez-Mota L, Estrada-Camarena E, López-Rubalcava C. Indorenate produces antidepressant-like actions in the rat forced swimming test via 5-HT1A receptors. Psychopharmacology (Berl). 2002 Dec;165(1):60-6. doi: 10.1007/s00213-002-1222-z. Epub 2002 Oct 23. PMID: 12474119.

3. Fernández-Guasti A, Escalante A, Hong E, Agmo A. Behavioural actions of the serotonergic anxiolytic indorenate. Pharmacol Biochem Behav. 1990 Sep;37(1):83-8. doi: 10.1016/0091-3057(90)90045-j. PMID: 1979877.