Imipramine hydrobromide

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 576627

CAS#: 67246-27-9

Description: Imipramine hydrobromide is a tricyclic antidepressant (TCA) of the dibenzazepine group.

Chemical Structure

img
Imipramine hydrobromide
CAS# 67246-27-9
Instruction

Theoretical Analysis

MedKoo Cat#: 576627
Name: Imipramine hydrobromide
CAS#: 67246-27-9
Chemical Formula: C19H25BrN2
Exact Mass: 360.12
Molecular Weight: 361.330
Elemental Analysis: C, 63.16; H, 6.97; Br, 22.11; N, 7.75

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Imipramine hydrobromide; Imipramine HBr

IUPAC/Chemical Name: 5H-Dibenz(b,f)azepine-5-propanamine, 10,11-dihydro-N,N-dimethyl-, hydrobromide (1:1)

InChi Key: XPAGIVLQSQMGIG-UHFFFAOYSA-N

InChi Code: InChI=1S/C19H24N2.BrH/c1-20(2)14-7-15-21-18-10-5-3-8-16(18)12-13-17-9-4-6-11-19(17)21;/h3-6,8-11H,7,12-15H2,1-2H3;1H

SMILES Code: Br.CN(C)CCCN1c2ccccc2CCc3ccccc13

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 361.33 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

1: Hearn L, Derry S, Phillips T, Moore RA, Wiffen PJ. Imipramine for neuropathic pain in adults. Cochrane Database Syst Rev. 2014 May 19;5:CD010769. doi: 10.1002/14651858.CD010769.pub2. Review. PubMed PMID: 24838845.

2: D'Agostino ML, Risser J, Robinson-Bostom L. Imipramine-induced hyperpigmentation: a case report and review of the literature. J Cutan Pathol. 2009 Jul;36(7):799-803. doi: 10.1111/j.1600-0560.2008.01121.x. Review. PubMed PMID: 19519613.

3: Dean CE, Grund FM. Imipramine-associated hyperpigmentation. Ann Pharmacother. 2003 Jun;37(6):825-8. Review. PubMed PMID: 12773071.

4: Hunsballe JM, Djurhuus JC. Clinical options for imipramine in the management of urinary incontinence. Urol Res. 2001 Apr;29(2):118-25. Review. PubMed PMID: 11396729.

5: Barros HM, Ferigolo M. Ethopharmacology of imipramine in the forced-swimming test: gender differences. Neurosci Biobehav Rev. 1998;23(2):279-86. Review. PubMed PMID: 9884121.