SIN44126
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 555944

CAS#: 1801344-12-6

Description: SIN44126 is a IRAK4 inhibitor, which was first described in patent WO 2015104688. This product has no formal name at the moment. For the convenience of communication, a temporary code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming).

Chemical Structure

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SIN44126
CAS# 1801344-12-6
Product data Instruction

Theoretical Analysis

MedKoo Cat#: 555944
Name: SIN44126
CAS#: 1801344-12-6
Chemical Formula: C24H25N7O5
Exact Mass: 491.19
Molecular Weight: 491.510
Elemental Analysis: C, 58.65; H, 5.13; N, 19.95; O, 16.28

Price and Availability

Size Price Availability Quantity
200mg USD 1850 2 Weeks
500mg USD 2850 2 Weeks
1g USD 3950 2 Weeks
2g USD 6450 2 Weeks
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Synonym: SIN44126; SIN-44126; SIN 44126; CAS-4948; CAS4948; CAS 4948;

IUPAC/Chemical Name: (S)-N-(5-(3-Hydroxypyrrolidin-1-yl)-2-morpholinooxazolo[4,5-b]pyridin-6-yl)-2-(2-methylpyridin-4-yl)oxazole-4-carboxamide

InChi Key: SJHNWSAWWOAWJH-INIZCTEOSA-N

InChi Code: InChI=1S/C24H25N7O5/c1-14-10-15(2-4-25-14)23-27-18(13-35-23)22(33)26-17-11-19-20(28-21(17)31-5-3-16(32)12-31)29-24(36-19)30-6-8-34-9-7-30/h2,4,10-11,13,16,32H,3,5-9,12H2,1H3,(H,26,33)/t16-/m0/s1

SMILES Code: O=C(C1=COC(C2=CC(C)=NC=C2)=N1)NC3=C(N4C[C@@H](O)CC4)N=C5C(OC(N6CCOCC6)=N5)=C3

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Product Data:
Product Data
Instruction:
View handling instruction
Biological target: SIN44126 is a IRAK4 inhibitor.
In vitro activity: To be determined
In vivo activity: To be determined

Preparing Stock Solutions

The following data is based on the product molecular weight 491.51 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol: To be determined
In vitro protocol: To be determined
In vivo protocol: To be determined

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