Fluoxetine succinate ester

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 575575

CAS#: 1026723-45-4

Description: Fluoxetine succinate ester is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. It is used for the treatment of major depressive disorder, obsessive–compulsive disorder, bulimia nervosa, panic disorder, and premenstrual dysphoric disorder.

Chemical Structure

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Fluoxetine succinate ester
CAS# 1026723-45-4
Instruction

Theoretical Analysis

MedKoo Cat#: 575575
Name: Fluoxetine succinate ester
CAS#: 1026723-45-4
Chemical Formula: C21H22F3NO4
Exact Mass: 409.15
Molecular Weight: 409.410
Elemental Analysis: C, 61.61; H, 5.42; F, 13.92; N, 3.42; O, 15.63

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Fluoxetine related compound C; Fluoxetine succinate ester

IUPAC/Chemical Name: Butanoic acid, 4-(methyl(3-phenyl-3-(4-(trifluoromethyl)phenoxy)propyl)amino)-4-oxo-

InChi Key: SAIPSZMZTANCFE-UHFFFAOYSA-N

InChi Code: 1S/C21H22F3NO4/c1-25(19(26)11-12-20(27)28)14-13-18(15-5-3-2-4-6-15)29-17-9-7-16(8-10-17)21(22,23)24/h2-10,18H,11-14H2,1H3,(H,27,28)

SMILES Code: CN(CCC(Oc1ccc(cc1)C(F)(F)F)c2ccccc2)C(=O)CCC(=O)O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 409.41 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Di Rosso ME, Palumbo ML, Genaro AM. Immunomodulatory effects of fluoxetine: A new potential pharmacological action for a classic antidepressant drug? Pharmacol Res. 2015 Nov 28. pii: S1043-6618(15)00279-0. doi: 10.1016/j.phrs.2015.11.021. [Epub ahead of print] Review. PubMed PMID: 26644208.

2: Purgato M, Gastaldon C, Papola D, Magni LR, Rossi G, Barbui C. Drug dose as mediator of treatment effect in antidepressant drug trials: the case of fluoxetine. Acta Psychiatr Scand. 2015 Jun;131(6):408-16. doi: 10.1111/acps.12381. Epub 2014 Dec 11. Review. PubMed PMID: 25495269.

3: Wang Y, Yu L, Xie J, Chen J, Wei Q. Comparative efficacies of fluoxetine and paroxetine in major depression across varying acute-phase treatment periods: a meta-analysis. Asia Pac Psychiatry. 2014 Dec;6(4):353-62. doi: 10.1111/appy.12106. Epub 2013 Oct 22. Review. PubMed PMID: 24150924.

4: Stewart AM, Grossman L, Nguyen M, Maximino C, Rosemberg DB, Echevarria DJ, Kalueff AV. Aquatic toxicology of fluoxetine: understanding the knowns and the unknowns. Aquat Toxicol. 2014 Nov;156:269-73. doi: 10.1016/j.aquatox.2014.08.014. Epub 2014 Sep 6. Review. PubMed PMID: 25245382.

5: Cristancho MA, Thase ME. Drug safety evaluation of olanzapine/fluoxetine combination. Expert Opin Drug Saf. 2014 Aug;13(8):1133-41. doi: 10.1517/14740338.2014.933804. Epub 2014 Jun 27. Review. PubMed PMID: 24972823.