Ederpin

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 463539

CAS#: 25635-68-1

Description: Ederpin is an antitumor agent.

Chemical Structure

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Ederpin
CAS# 25635-68-1
Instruction

Theoretical Analysis

MedKoo Cat#: 463539
Name: Ederpin
CAS#: 25635-68-1
Chemical Formula: C10H15N6O3P
Exact Mass: 298.09
Molecular Weight: 298.243
Elemental Analysis: C, 40.27; H, 5.07; N, 28.18; O, 16.09; P, 10.39

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Ederpin; Ederpine; Preparation 631; Preparation-631;

IUPAC/Chemical Name: 1-(di(aziridin-1-yl)phosphoryl)-3-(5-methoxypyrimidin-2-yl)urea

InChi Key: DQRQBRDDSALHQM-UHFFFAOYSA-N

InChi Code: InChI=1S/C10H15N6O3P/c1-19-8-6-11-9(12-7-8)13-10(17)14-20(18,15-2-3-15)16-4-5-16/h6-7H,2-5H2,1H3,(H2,11,12,13,14,17,18)

SMILES Code: COc1cnc(NC(NP(N2CC2)(N3CC3)=O)=O)nc1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 298.24 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Loboda IP, Mironiuk SI, Bezverkhiĭ VD, Kapustnik VI. Patogeneticheskoe lechenie i prognosticheskie kriterii u bol'nykh s pigmentnymi opukholiami [Pathogenetic treatment and prognostic criteria in patients with pigmented tumors]. Klin Khir. 1990;(12):46-7. Russian. PMID: 2082095.

2: Klimenko IA, Goĭkhberg MI, Zaparin VK, Iaremko VN, Sakalo VS. Kompleksnoe lechenie raka mochevogo puzyria s pred- i posleoperatsionnoĭ khimioterapieĭ [Complex treatment of bladder cancer with pre- and postoperative chemotherapy]. Urol Nefrol (Mosk). 1987 Jan-Feb;(1):26-8. Russian. PMID: 3564196.

3: Timoshenko IaG, Suptelo LP, Petunin IuI, Kulik GI, Kobylinskaia TS. Primenenie matematicheskikh metodov v farmakokinetike protivo-opukholevykh preparatov dlia prognozirovaniia ikh kontsentratsii v organakh i tkaniakh [Use of mathematical methods in the pharmacokinetics of antitumor preparations for predicting their concentration in organs and tissues]. Dokl Akad Nauk SSSR. 1983;268(2):492-5. Russian. PMID: 6832008.