TC NTR1 17
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 574427

CAS#: 1146757-96-1

Description: TC NTR1 17 is a non-peptide neurotensin receptor 1 (NTS1) partial agonist.

Chemical Structure

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TC NTR1 17
CAS# 1146757-96-1
Instruction

Theoretical Analysis

MedKoo Cat#: 574427
Name: TC NTR1 17
CAS#: 1146757-96-1
Chemical Formula: C27H27ClN4O5
Exact Mass: 522.17
Molecular Weight: 522.990
Elemental Analysis: C, 62.01; H, 5.20; Cl, 6.78; N, 10.71; O, 15.30

Price and Availability

Size Price Availability Quantity
10mg USD 440 2 Weeks
50mg USD 1525 2 Weeks
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Synonym: ML 301 analog, TC NTR1 17

IUPAC/Chemical Name: N-[[1-(7-Chloro-4-quinolinyl)-5-(2,6-dimethoxyphenyl)-1H-pyrazol-3-yl]carbonyl]-L-leucine

InChi Key: ZQUSYVORYNBGLG-FQEVSTJZSA-N

InChi Code: InChI=1S/C27H27ClN4O5/c1-15(2)12-20(27(34)35)30-26(33)19-14-22(25-23(36-3)6-5-7-24(25)37-4)32(31-19)21-10-11-29-18-13-16(28)8-9-17(18)21/h5-11,13-15,20H,12H2,1-4H3,(H,30,33)(H,34,35)/t20-/m0/s1

SMILES Code: CC(C)C[C@@H](C(O)=O)NC(C1=NN(C2=CC=NC3=CC(Cl)=CC=C23)C(C4=C(OC)C=CC=C4OC)=C1)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 522.99 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1. Hershberger et al (2014) Imidazole-derived agonists for the neurotensin 1 receptor. Bioorg.Med.Chem.Lett. 24 262 PMID: 24332089