Taurine
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MedKoo CAT#: 574209

CAS#: 107-35-7

Description: Taurine is a sulfur-containing amino acid with antioxidative, anticancer, cardioprotective, and neuroprotective properties. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH) radicals and decreases the viability of MCF-7 and MDA-MB-231 human breast cancer cells. It prevents left ventricular dysfunction in late-stage Duchenne muscular dystrophy and prevents neurotoxicity induced by amyloid-β (Aβ) or the glutamate receptor agonists glutamate, NMDA --- an effect that can be blocked by the GABAA receptor antagonist picrotoxin.

Chemical Structure

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Taurine
CAS# 107-35-7
Instruction

Theoretical Analysis

MedKoo Cat#: 574209
Name: Taurine
CAS#: 107-35-7
Chemical Formula: C2H7NO3S
Exact Mass: 125.01
Molecular Weight: 125.140
Elemental Analysis: C, 19.20; H, 5.64; N, 11.19; O, 38.35; S, 25.62

Price and Availability

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25g USD 195
500g USD 490
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Synonym: β-Aminoethylsulfonic Acid, NSC 32428, Taurine

IUPAC/Chemical Name: 2-amino-ethanesulfonic acid

InChi Key: XOAAWQZATWQOTB-UHFFFAOYSA-N

InChi Code: InChI=1S/C2H7NO3S/c3-1-2-7(4,5)6/h1-3H2,(H,4,5,6)

SMILES Code: OS(CCN)(=O)=O

Appearance: A crystalline solid

Purity: >95% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 125.14 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1. Schaffer, S., and Kim, H.W. Effects and mechanisms of taurine as a therapeutic agent. Biomol. Ther. (Seoul) 26(3), 225-241 (2018).

2. Choi, E.-J., Tang, Y., Lee, C.B., et al. Investigation of antioxidant and anticancer potential of taurine by means of multiple chemical and biological assays. Taurine 9 (2018).

3. Mele, A., Manturano, P., De Bellis, M., et al. A long-term treatment with taurine prevents cardiac dysfunction in mdx mice. Transl. Res. 204, 82-99 (2019).

4. Louzada, P.R., Lima, A.C.P., Mendonça-Silva, D.L., et al. Taurine prevents the neurotoxicity of ß-amyloid and glutamate receptor agonists: Activation of GABA receptors and possible implications for Alzheimer’s disease and other neurological disorders. FASEB J. 18(3), 511-518 (2004).