STY-BODIPY
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 574056

CAS#: 2383063-37-2

Description: STY-BODIPY is a styrene-conjugated fluorogenic probe for radical-trapping antioxidant (RTA) activity. Co-autoxidation of the STY-BODIPY signal carrier and a hydrocarbon co-substrate can be quantified by monitoring the loss of absorbance at 571 nm. STY-BODIPY has been used to measure the activity of RTAs, as well as the kinetics and stoichiometry of RTA reactions in cell-free assays.

Chemical Structure

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STY-BODIPY
CAS# 2383063-37-2
Product data Instruction

Theoretical Analysis

MedKoo Cat#: 574056
Name: STY-BODIPY
CAS#: 2383063-37-2
Chemical Formula: C19H17BF2N2
Exact Mass: 322.15
Molecular Weight: 322.170
Elemental Analysis: C, 70.84; H, 5.32; B, 3.36; F, 11.79; N, 8.70

Price and Availability

Size Price Availability Quantity
1mg USD 450 2 weeks
5mg USD 1100 2 weeks
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Synonym: STY-BODIPY, Styrene-BODIPY, Styrene-conjugated BODIPY

IUPAC/Chemical Name: (E)-5,5-difluoro-1,3-dimethyl-7-styryl-5H-4l4,5l4-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinine

InChi Key: HCSMCBDAQPKMBB-CMDGGOBGSA-N

InChi Code: InChI=1S/C19H17BF2N2/c1-14-12-15(2)23-19(14)13-18-11-10-17(24(18)20(23,21)22)9-8-16-6-4-3-5-7-16/h3-13H,1-2H3/b9-8+

SMILES Code: CC(C=C1C)=[N+](C1=C2)[B-](F)(F)N3C2=CC=C3/C=C/C4=CC=CC=C4

Appearance: A solution in benzene

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in benzene

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info: λmax: 240, 313, 562 nm

Product Data:
Product Data
Instruction:
View handling instruction
Biological target: STY-BODIPY is a styrene-conjugated fluorogenic probe for RTA activity.
In vitro activity: To be determined
In vivo activity: To be determined

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
Benzene 1.0 3.10

Preparing Stock Solutions

The following data is based on the product molecular weight 322.17 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol: To be determined
In vitro protocol: To be determined
In vivo protocol: To be determined

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1. Haidasz, E.A., Van Kessel, A.T.M., and Pratt, D.A. A continuous visible light spectrophotometric approach to accurately determine the reactivity of radical-trapping antioxidants. J. Org. Chem. 81(3), 737-744 (2016).

2. Shah, R., Shchepinov, M.S., and Pratt, D.A. Resolving the role of lipoxygenases in the initiation and execution of ferroptosis. ACS Cent. Sci. 4(3), 387-396 (2018).

3. Chauvin, J.-P.R., Haidasz, E.A., Griesser, M., et al. Polysulfide-1-oxides react with peroxyl radicals as quickly as hindered phenolic antioxidants and do so by a surprising concerted homolytic substitution. Chem. Sci. 7(10), 6347-6356 (2016).