WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 533082


Description: EE02 is a Novel EGFR/Eps8 complex inhibitor, promoting apoptotic cell death and demonstrating promising antitumor effects in breast cancer and NSCLC.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 533082
Name: EE02
Chemical Formula: C44H54N4O6S
Exact Mass: 766.3764
Molecular Weight: 766.998
Elemental Analysis: C, 68.90; H, 7.10; N, 7.30; O, 12.52; S, 4.18

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: EE02; EE-02; EE 02

IUPAC/Chemical Name: 3,3'-((Sulfonylbis(4,1-phenylene))bis(oxy))bis(1-(4-((Z)-3-phenylallyl)piperazin-1-yl)propan-2-ol)


InChi Code: InChI=1S/C44H54N4O6S/c49-39(33-47-29-25-45(26-30-47)23-7-13-37-9-3-1-4-10-37)35-53-41-15-19-43(20-16-41)55(51,52)44-21-17-42(18-22-44)54-36-40(50)34-48-31-27-46(28-32-48)24-8-14-38-11-5-2-6-12-38/h1-22,39-40,49-50H,23-36H2/b13-7-,14-8-


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 766.998 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

Molarity Calculator

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1: Li M, Yang J, Zhang L, Tu S, Zhou X, Tan Z, Zhou W, He Y, Li Y. A
low-molecular-weight compound exerts anticancer activity against breast and lung
cancers by disrupting EGFR/Eps8 complex formation. J Exp Clin Cancer Res. 2019
May 22;38(1):211. doi: 10.1186/s13046-019-1207-y. PubMed PMID: 31118055; PubMed
Central PMCID: PMC6532146.