WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 581969
CAS#: 119290-00-5
Description: 10-Propoxydecanoic acid is a oxygen substituted analog of myristic acid.
MedKoo Cat#: 581969
Name: 10-Propoxydecanoic acid
CAS#: 119290-00-5
Chemical Formula: C13H26O3
Exact Mass: 230.19
Molecular Weight: 230.35
Elemental Analysis: C, 67.79; H, 11.38; O, 20.84
This product is not in stock, which may be available by custom synthesis.
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Synonym: 10-Propoxydecanoic acid; 11-Oxatetradecanoic acid; 11-Oxymyristic acid.
IUPAC/Chemical Name: 10-propoxydecanoic acid
InChi Key: HSRAJJQTYQHRSA-UHFFFAOYSA-N
InChi Code: InChI=1S/C13H26O3/c1-2-11-16-12-9-7-5-3-4-6-8-10-13(14)15/h2-12H2,1H3,(H,14,15)
SMILES Code: C(CCCCCCCCCOCCC)(=O)O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 230.35 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Doering TL, Lu T, Werbovetz KA, Gokel GW, Hart GW, Gordon JI, Englund PT. Toxicity of myristic acid analogs toward African trypanosomes. Proc Natl Acad Sci U S A. 1994 Oct 11;91(21):9735-9. PubMed PMID: 7937882; PubMed Central PMCID: PMC44891.
2: Ross CA, Taylor AM. Trypanocidal activity of a myristic acid analog in axenic cultures of Trypanosoma evansi. Parasitol Res. 1994;80(2):147-53. PubMed PMID: 8202455.
3: Doering TL, Raper J, Buxbaum LU, Adams SP, Gordon JI, Hart GW, Englund PT. An analog of myristic acid with selective toxicity for African trypanosomes. Science. 1991 Jun 28;252(5014):1851-4. PubMed PMID: 1829548.
4: Duronio RJ, Jackson-Machelski E, Heuckeroth RO, Olins PO, Devine CS, Yonemoto W, Slice LW, Taylor SS, Gordon JI. Protein N-myristoylation in Escherichia coli: reconstitution of a eukaryotic protein modification in bacteria. Proc Natl Acad Sci U S A. 1990 Feb;87(4):1506-10. PubMed PMID: 2406721; PubMed Central PMCID: PMC53504.
5: Bryant ML, Heuckeroth RO, Kimata JT, Ratner L, Gordon JI. Replication of human immunodeficiency virus 1 and Moloney murine leukemia virus is inhibited by different heteroatom-containing analogs of myristic acid. Proc Natl Acad Sci U S A. 1989 Nov;86(22):8655-9. PubMed PMID: 2813417; PubMed Central PMCID: PMC298346.
6: Heuckeroth RO, Gordon JI. Altered membrane association of p60v-src and a murine 63-kDa N-myristoyl protein after incorporation of an oxygen-substituted analog of myristic acid. Proc Natl Acad Sci U S A. 1989 Jul;86(14):5262-6. PubMed PMID: 2501783; PubMed Central PMCID: PMC297601.
