Cinnamic acid, hydrazide

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 573610

CAS#: 3538-69-0

Description: Cinnamic acid, hydrazide is an unsaturated carboxylic acid and precursor to aspartame via enzyme-catalysed amination to phenylalanine. Cinnamic acid may be useful in prevention or treatment of Diabetes through various mechanism of actions including stimulation of insulin secretion, improvement of pancreatic β-cell functionality, inhibition of hepatic gluconeogenesis, enhanced glucose uptake, increased insulin signaling pathway, delay of carbohydrate digestion and glucose absorption, and inhibition of protein glycation and insulin fibrillation.

Chemical Structure

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Cinnamic acid, hydrazide
CAS# 3538-69-0
Instruction

Theoretical Analysis

MedKoo Cat#: 573610
Name: Cinnamic acid, hydrazide
CAS#: 3538-69-0
Chemical Formula: C9H10N2O
Exact Mass: 162.08
Molecular Weight: 162.190
Elemental Analysis: C, 66.65; H, 6.21; N, 17.27; O, 9.86

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: AI3-62695; Cinnamic acid, hydrazide; Cinnamoyl hydrazide; Cinnamoylhydrazine

IUPAC/Chemical Name: 2-Propenoic acid, 3-phenyl-, hydrazide (9CI)

InChi Key: MTWDGUWQZYXGTQ-VOTSOKGWSA-N

InChi Code: 1S/C9H10N2O/c10-11-9(12)7-6-8-4-2-1-3-5-8/h1-7H,10H2,(H,11,12)/b7-6+

SMILES Code: c1(\C=C\C(NN)=O)ccccc1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 162.19 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Adisakwattana S. Cinnamic Acid and Its Derivatives: Mechanisms for Prevention and Management of Diabetes and Its Complications. Nutrients. 2017 Feb 21;9(2). pii: E163. doi: 10.3390/nu9020163. Review. PubMed PMID: 28230764; PubMed Central PMCID: PMC5331594.

2: Tang Y, Zheng M, Chen YL, Chen J, He Y. Pharmacokinetic Effects of Cinnamic Acid, Amygdalin, Glycyrrhizic Acid and Liquiritin on Ephedra Alkaloids in Rats. Eur J Drug Metab Pharmacokinet. 2017 Jun;42(3):527-535. doi: 10.1007/s13318-016-0368-8. PubMed PMID: 27514823.

3: Mielecki M, Lesyng B. Cinnamic Acid Derivatives as Inhibitors of Oncogenic Protein Kinases--Structure, Mechanisms and Biomedical Effects. Curr Med Chem. 2016;23(10):954-82. Review. PubMed PMID: 26980568.