C-178
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MedKoo CAT#: 564707

CAS#: 329198-87-0

Description: C-178 is a covalent inhibitor of STING, blocking palmitoylation-induced clustering of STING.

Chemical Structure

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C-178
CAS# 329198-87-0
Product data Instruction

Theoretical Analysis

MedKoo Cat#: 564707
Name: C-178
CAS#: 329198-87-0
Chemical Formula: C17H10N2O5
Exact Mass: 322.06
Molecular Weight: 322.280
Elemental Analysis: C, 63.36; H, 3.13; N, 8.69; O, 24.82

Price and Availability

Size Price Availability Quantity
5mg USD 90 Ready to ship
25mg USD 295 Ready to ship
50mg USD 450 Ready to ship
100mg USD 650 Ready to ship
200mg USD 950 Ready to ship
500mg USD 1650 Ready to ship
1g USD 2950 Ready to ship
2g USD 5250 Ready to ship
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Synonym: C178; C 178; C-178, STING inhibitor C-178

IUPAC/Chemical Name: N-(Dibenzo[b,d]furan-3-yl)-5-nitrofuran-2-carboxamide

InChi Key: URUVDCCYSJEGQQ-UHFFFAOYSA-N

InChi Code: InChI=1S/C17H10N2O5/c20-17(14-7-8-16(24-14)19(21)22)18-10-5-6-12-11-3-1-2-4-13(11)23-15(12)9-10/h1-9H,(H,18,20)

SMILES Code: O=C(C1=CC=C([N+]([O-])=O)O1)NC2=CC=C3C(OC4=CC=CC=C34)=C2

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target: C-178 is a covalent STING inhibitor.
In vitro activity: To be determined
In vivo activity: To be determined

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 2.0 6.21

Preparing Stock Solutions

The following data is based on the product molecular weight 322.28 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol: To be determined
In vitro protocol: To be determined
In vivo protocol: To be determined

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