WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 564707
CAS#: 329198-87-0
Description: C-178 is a covalent inhibitor of STING, blocking palmitoylation-induced clustering of STING.
MedKoo Cat#: 564707
Name: C-178
CAS#: 329198-87-0
Chemical Formula: C17H10N2O5
Exact Mass: 322.059
Molecular Weight: 322.28
Elemental Analysis: C, 63.36; H, 3.13; N, 8.69; O, 24.82
Synonym: C178; C 178; C-178
IUPAC/Chemical Name: N-(Dibenzo[b,d]furan-3-yl)-5-nitrofuran-2-carboxamide
InChi Key: URUVDCCYSJEGQQ-UHFFFAOYSA-N
InChi Code: InChI=1S/C17H10N2O5/c20-17(14-7-8-16(24-14)19(21)22)18-10-5-6-12-11-3-1-2-4-13(11)23-15(12)9-10/h1-9H,(H,18,20)
SMILES Code: O=C(C1=CC=C([N+]([O-])=O)O1)NC2=CC=C3C(OC4=CC=CC=C34)=C2
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 322.28 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
