Dimethicone 350

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 581277

CAS#: 9006-65-9

Description: Dimethicone 350 is a silicone oil consisting of a mixture of fully methylated linear siloxane polymers end-blocking with trimethylsiloxy units. Commonly used in skin and hair products.


Chemical Structure

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Dimethicone 350
CAS# 9006-65-9

Theoretical Analysis

MedKoo Cat#: 581277
Name: Dimethicone 350
CAS#: 9006-65-9
Chemical Formula: C₃H₉Si(C₂H₆OSi)nCH₃
Exact Mass: 0.00
Molecular Weight: 0.000
Elemental Analysis:

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: Dimethicone 350; Dimeticona; Dimethicone; Dimeticonum; Polysilane; Ophtasiloxane;

IUPAC/Chemical Name: alpha-(Trimethylsilyl)-omega-methylpoly(oxy(dimethylsilylene)), mixture with silicon dioxide

InChi Key:

InChi Code:

SMILES Code:

Appearance: Liquid

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Product Data:
Biological target: Dimethicone 350 is a silicone oil consisting of a mixture of fully methylated linear siloxane polymers end-blocking with trimethylsiloxy units.
In vitro activity: TBD
In vivo activity: TBD

Preparing Stock Solutions

The following data is based on the product molecular weight 0.00 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol: TBD
In vitro protocol: TBD
In vivo protocol: TBD

Molarity Calculator

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1: Sugar HS, Okamura ID. Ocular findings six years after intravitreal silicone injection. Arch Ophthalmol. 1976 Apr;94(4):612-5. PubMed PMID: 1267641.