Ac4ManNAz
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 563796

CAS#: 361154-30-5

Description: Ac4ManNAz is a novel probe for metabolic labeling of sialoglycans, selectively imaging polysialic acids in neurons. treatment with 50 μM Ac4ManNAz led to the reduction of major cellular functions, including energy generation capacity, cellular infiltration ability and channel activity. Interestingly, 10 μM Ac4ManNAz showed the least effect on cellular systems and had a sufficient labeling efficiency for cell labeling, tracking and proteomic analysis. Based on our results, we suggest 10 μM as the optimum concentration of Ac4ManNAz for in vivo cell labeling and tracking.

Chemical Structure

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Ac4ManNAz
CAS# 361154-30-5
Instruction

Theoretical Analysis

MedKoo Cat#: 563796
Name: Ac4ManNAz
CAS#: 361154-30-5
Chemical Formula: C16H22N4O10
Exact Mass: 430.13
Molecular Weight: 430.370
Elemental Analysis: C, 44.65; H, 5.15; N, 13.02; O, 37.17

Price and Availability

Size Price Availability Quantity
25mg USD 485 2 Weeks
50mg USD 850 2 Weeks
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Synonym: Ac4ManNAz; Ac 4ManNAz; Ac-4ManNAz; Ac4Man-NAz; Ac4-Man-NAz; Ac4-ManNAz; N-Azidoacetylmannosamine-tetraacylated

IUPAC/Chemical Name: Peracetylated N-azidoacetyl-d-mannosamine

InChi Key: HGMISDAXLUIXKM-LIADDWGISA-N

InChi Code: InChI=1S/C16H22N4O10/c1-7(21)26-6-11-14(27-8(2)22)15(28-9(3)23)13(16(30-11)29-10(4)24)19-12(25)5-18-20-17/h11,13-16H,5-6H2,1-4H3,(H,19,25)/t11-,13+,14-,15-,16?/m1/s1

SMILES Code: O=C(C)OC[C@H]1OC(OC(C)=O)[C@@H](NC(CN=[N+]=[N-])=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O

Appearance: Solid powder

Purity: >95% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 430.37 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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