Prodolic acid

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 593127

CAS#: 36505-82-5

Description: Prodolic acid is an Anti-Inflammatory agent.

Chemical Structure

img
Prodolic acid
CAS# 36505-82-5
Instruction

Theoretical Analysis

MedKoo Cat#: 593127
Name: Prodolic acid
CAS#: 36505-82-5
Chemical Formula: C16H19NO3
Exact Mass: 273.14
Molecular Weight: 273.330
Elemental Analysis: C, 70.31; H, 7.01; N, 5.12; O, 17.56

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Prodolic acid; NSC 299133; NSC-299133; NSC299133

IUPAC/Chemical Name: Pyrano(3,4-b)indole-1-acetic acid, 1,3,4,9-tetrahydro-1-propyl-

InChi Key: IZGMROSLQHXRDZ-UHFFFAOYSA-N

InChi Code: InChI=1S/C16H19NO3/c1-2-8-16(10-14(18)19)15-12(7-9-20-16)11-5-3-4-6-13(11)17-15/h3-6,17H,2,7-10H2,1H3,(H,18,19)

SMILES Code: O=C(O)CC1(CCC)OCCC2=C1NC3=C2C=CC=C3

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 273.33 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

1: Robinson WT, Kraml M, Greselin E, Dvornik D. Prodolic acid: analysis and disposition studies in rats and dogs. Xenobiotica. 1977 Jun;7(6):329-37. PubMed PMID: 305689.

2: Greenberg R. Some pharmacological effects of prodolic acid, a new anti-inflammatory compound, indicative of inhibition of prostaglandin synthesis. Can J Physiol Pharmacol. 1975 Feb;53(1):186-9. PubMed PMID: 1139444.

3: Demerson CA, Humber LG, Dobson TA, Martel RR. Chemistry and antiinflammatory activities of prodolic-acid and related 1,3,4,9-tetrahydropyrano[3,4-b]indole-1-alkanoic acids. 1. J Med Chem. 1975 Feb;18(2):189-91. PubMed PMID: 1120985.

4: Martel RR, Klicius J, Herr F. Investigation of 1,3,4,9-Tetrahydro-1-popylpyrano [3,4-b] indole-1-acetic acid (prodolic acid), a new non-steroidal anti-inflammatory agent, in rats. Agents Actions. 1974 Dec;4(5):370-6. PubMed PMID: 4463721.