Sarcinapterin

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 461804

CAS#: 89157-12-0

Description: Sarcinapterin is a coenzyme isolated from Methanosarcina barkeri.

Chemical Structure

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Sarcinapterin
CAS# 89157-12-0
Instruction

Theoretical Analysis

MedKoo Cat#: 461804
Name: Sarcinapterin
CAS#: 89157-12-0
Chemical Formula: C35H48N7O19P
Exact Mass: 901.27
Molecular Weight: 901.770
Elemental Analysis: C, 46.62; H, 5.37; N, 10.87; O, 33.71; P, 3.43

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: Sarcinapterin;

IUPAC/Chemical Name: (2-(((((2R,3S,4R,5S)-5-((5-(4-((1-(2-amino-7-methyl-4-oxo-1,4-dihydropteridin-6-yl)ethyl)amino)phenyl)-2,3,4-trihydroxypentyl)oxy)-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(hydroxy)phosphoryl)oxy)-4-carboxybutanoyl)glutamic acid

InChi Key: ZZZXRXDSTUEPEK-GQFBUSLDSA-N

InChi Code: InChI=1S/C35H48N7O19P/c1-14(25-15(2)38-30-26(40-25)32(53)42-35(36)41-30)37-17-5-3-16(4-6-17)11-19(43)27(49)20(44)12-58-34-29(51)28(50)22(60-34)13-59-62(56,57)61-21(8-10-24(47)48)31(52)39-18(33(54)55)7-9-23(45)46/h3-6,14,18-22,27-29,34,37,43-44,49-51H,7-13H2,1-2H3,(H,39,52)(H,45,46)(H,47,48)(H,54,55)(H,56,57)(H3,36,38,41,42,53)/t14?,18?,19?,20?,21?,22-,27?,28-,29-,34+/m1/s1

SMILES Code: OC(C(C(CO[C@@H]1[C@@H]([C@@H]([C@@H](COP(O)(OC(C(NC(C(O)=O)CCC(O)=O)=O)CCC(O)=O)=O)O1)O)O)O)O)CC2=CC=C(NC(C3=C(C)N=C4NC(N)=NC(C4=N3)=O)C)C=C2

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 901.77 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Gorris LG, van der Drift C. Cofactor contents of methanogenic bacteria reviewed. Biofactors. 1994 May;4(3-4):139-45. PubMed PMID: 7916957.

2: Raemakers-Franken PC, Kortstee AJ, van der Drift C, Vogels GD. Methanogenesis involving a novel carrier of C1 compounds in Methanogenium tationis. J Bacteriol. 1990 Feb;172(2):1157-9. PubMed PMID: 2105296; PubMed Central PMCID: PMC208554.

3: Raemakers-Franken PC, Voncken FG, Korteland J, Keltjens JT, van der Drift C, Vogels GD. Structural characterization of tatiopterin, a novel pterin isolated from Methanogenium tationis. Biofactors. 1989 Dec;2(2):117-22. PubMed PMID: 2624671.

4: White RH. Purine biosynthesis in the domain Archaea without folates or modified folates. J Bacteriol. 1997 May;179(10):3374-7. PubMed PMID: 9150241; PubMed Central PMCID: PMC179124.

5: Gorris LG, de Kok TM, Kroon BM, van der Drift C, Vogels GD. Relationship between Methanogenic Cofactor Content and Maximum Specific Methanogenic Activity of Anaerobic Granular Sludges. Appl Environ Microbiol. 1988 May;54(5):1126-30. PubMed PMID: 16347625; PubMed Central PMCID: PMC202615.

6: van Beelen P, Labro JF, Keltjens JT, Geerts WJ, Vogels GD, Laarhoven WH, Guijt W, Haasnoot CA. Derivatives of methanopterin, a coenzyme involved in methanogenesis. Eur J Biochem. 1984 Mar 1;139(2):359-65. PubMed PMID: 6698019.