Runanine

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 461564

CAS#: 100485-12-9

Description: Runanine is a hasubanan alkaloid.

Chemical Structure

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Runanine
CAS# 100485-12-9
Instruction

Theoretical Analysis

MedKoo Cat#: 461564
Name: Runanine
CAS#: 100485-12-9
Chemical Formula: C21H27NO5
Exact Mass: 373.19
Molecular Weight: 373.440
Elemental Analysis: C, 67.54; H, 7.29; N, 3.75; O, 21.42

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Runanine;

IUPAC/Chemical Name: (4bS,8aS)-2,3,7,8-tetramethoxy-11-methyl-9,10-dihydro-8a,4b-(epiminoethano)phenanthren-6(5H)-one

InChi Key: FFKKIUDOINNTGR-LEWJYISDSA-N

InChi Code: InChI=1S/C21H27NO5/c1-22-9-8-20-12-15(23)18(26-4)19(27-5)21(20,22)7-6-13-10-16(24-2)17(25-3)11-14(13)20/h10-11H,6-9,12H2,1-5H3/t20-,21+/m0/s1

SMILES Code: O=C1C[C@@]2(CCN3C)C4=CC(OC)=C(OC)C=C4CC[C@@]23C(OC)=C1OC

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 373.44 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Herzon SB, Calandra NA, King SM. Efficient entry to the hasubanan alkaloids: first enantioselective total syntheses of (-)-hasubanonine, (-)-runanine, (-)-delavayine, and (+)-periglaucine B. Angew Chem Int Ed Engl. 2011 Sep 12;50(38):8863-6. doi: 10.1002/anie.201102226. Epub 2011 Jun 3. PubMed PMID: 21638524.

2: King SM, Herzon SB. The Hasubanan and Acutumine Alkaloids. Alkaloids Chem Biol. 2014;73:161-222. doi: 10.1016/B978-0-12-411565-1.00003-2. Epub 2013 Dec 25. PubMed PMID: 26521650.

3: Nielsen DK, Nielsen LL, Jones SB, Toll L, Asplund MC, Castle SL. Synthesis of isohasubanan alkaloids via enantioselective ketone allylation and discovery of an unexpected rearrangement. J Org Chem. 2009 Feb 6;74(3):1187-99. doi: 10.1021/jo802370v. PubMed PMID: 19072324.