Fenipentol | CAS#583-03-9 | stimulates plasma secretion

Fenipentol
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WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 592637

CAS#: 583-03-9

Description: Fenipentol stimulates plasma secretion & exocrine pancreatic secretion.

Chemical Structure

Fenipentol

CAS# 583-03-9

Instruction

Theoretical Analysis

MedKoo Cat#: 592637
Name: Fenipentol
CAS#: 583-03-9
Chemical Formula: C11H16O
Exact Mass: 164.12
Molecular Weight: 164.250
Elemental Analysis: C, 80.44; H, 9.82; O, 9.74

Price and Availability

Size	Price	Availability	Quantity
25mg	USD 285	2 Weeks
Bulk inquiry Welcome, Customer: Please do not inquire quote if your intended use is for a patient since our products are for research use and for chemical synthesis use, not for human use . For in-stock products, we listed price in the web page. You may inquire prices for which sizes were not listed. If no price is listed, this means the product is not in stock at the moment, which may be available via custom synthesis. For cost-effective reason, minimum order of 1g is requested (typically very expensive). The lead time is usually 2-4 months. Quote of less than 1g will not be provided. MedKoo may not offer quote for below reasons: (1) current available synthetic method appears to be extremely expensive which is obviously not affordable to most customers; (2) Key raw material to make the product is temporally not available; (3) DEA controlled substances; (4) the product is under patent protection in customer’s country.

Synonym: Fenipentol

IUPAC/Chemical Name: alpha-Butylbenzyl alcohol

InChi Key: OVGORFFCBUIFIA-UHFFFAOYSA-N

InChi Code: InChI=1S/C11H16O/c1-2-3-9-11(12)10-7-5-4-6-8-10/h4-8,11-12H,2-3,9H2,1H3

SMILES Code: CCCCC(O)C1=CC=CC=C1

Appearance: Liquid

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Instruction:

View handling instruction

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 164.25 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Li Y, Yang W, Li W, Wu T. Unveiling differential mechanisms of chuanxiong cortex and pith in the treatment of coronary heart disease using SPME-GC×GC-MS and network pharmacology. J Pharm Biomed Anal. 2023 Sep 20;234:115540. doi: 10.1016/j.jpba.2023.115540. Epub 2023 Jun 21. PMID: 37418871.

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5: Chey WY, Millikan L, Lee KY, Watanabe S, Shiratori K, Takeuchi T. Effect of 1-phenylpentanol on release of secretin and exocrine pancreatic secretion in dogs and humans. Gastroenterology. 1983 Jun;84(6):1578-84. PMID: 6840488.

6: Endo K, Koizumi M, Kanazawa Y, Yoshida S, Miura M, Kanno T, Koizumi F, Goto Y. Plasma secretin level and exocrine pancreatic secretion in response to intraduodenal infusion of 1-phenyl-1-hydroxy-n-pentane and HCl by using a new four lumen tube. Tohoku J Exp Med. 1980 Aug;131(4):363-71. doi: 10.1620/tjem.131.363. PMID: 7466802.

7: KOSS FW, BEISENHERZ G, HUBER I, EISELE M. STOFFWECHSELVERSUCHE MIT 1-PHENYL-1-HYDROXY-N-PENTAN [METABOLISM EXPERIMENTS WITH 1-PHENYL-1-HYDROXY-N- PENTANE]. Arzneimittelforschung. 1964 Mar;14:195-8. German. PMID: 14235984.

8: Endo K, Koizumi M, Kanazawa Y, Yoshida S, Miura M, Kanno T, Koizumi F, Gotoh Y. [Plasma secretin level and exocrine pancreatic secretion in response to intraduodenal infusion of 1-phenyl-1-hydroxy-n-pentane and HCL by using new four lumen tube (author's transl)]. Nihon Shokakibyo Gakkai Zasshi. 1979 Oct;76(10):2017-23. Japanese. PMID: 529499.

9: VILLANUEVADIAZ A, BELMONTEVICENTE A, PEREZSANCHEZ C, RODRIGUEZBUJAN L. ACCION DEL 1-FENIL-1-HIDROXI-N-PENTANO Y BROMURO DEL ESTER-BETA-(DIMETIL-N-OCTIL- AMONIO)-ETIL-BENCILICO SOBRE LA FUNCION HEPATICA, ESTUDIADA CON ROSA DE BENGALA RADIACTIVO [ACTION OF 1-PHENYL-1-HYDROXY-N-PENTANE AND 2-(DIMETHYL-N- OCTYLAMMONIUM)-ETHYL BENZILATE BROMIDE ON HEPATIC FUNCTION, STUDIED WITH RADIOACTIVE ROSE BENGAL]. Rev Clin Esp. 1964 Feb 15;92:169-76. Spanish. PMID: 14151558.

10: KOSS FW, BEISENHERZ G, CHUCHRA U, HUBER I. DIE CHOLERETISCHE WIRKUNG DES 1-PHENYL-1-HYDROXY-N-PENTANS [THE CHOLERETIC EFFECT OF 1-PHENYL-1-HYDROXY-N- PENTANE]. Arzneimittelforschung. 1964 Mar;14:191-5. German. PMID: 14235983.

11: ENGELHORN R. [The choleretic effect of 1-phenyl-1-hydroxy-n-pentane]. Arzneimittelforschung. 1960 Apr;10:255-60. German. PMID: 13820347.

12: VANCINI B. [Clinico-experimental study on a new substance with choleretic action (1-phenyl-1-hydroxy-n-pentane) associated with a spasmolytic having double atropine- and papaverine-like action in patients with hepatobiliary diseases]. Minerva Med. 1962 May 12;53:1478-86. Italian. PMID: 13924674.

13: DIOGUARDI N, COSTA F, MANNUCCI PM. [Considerations on the cholecystokinetic activity of 1-phenyl-1-hydroxy-N-pentane]. Riforma Med. 1963 May 25;77:561-4. Italian. PMID: 14027994.

14: Otsuki M, Sakamoto C, Ohki A, Yuu H, Baba S. Effect of intraduodenal instillation of 1-phenyl-1-hydroxy-n-pentane on pancreatic exocrine secretions and immunoreactive secretion release in the rat. Horm Metab Res. 1981 Feb;13(2):80-4. doi: 10.1055/s-2007-1019179. PMID: 6164622.

15: Otsuki M, Sakamoto C, Ohki A, Yuu H, Maeda M, Baba S. Pancreatic exocrine secretion and immunoreactive secretin release after intraduodenal instillation of 1-phenyl-1-hydroxy-n-pentane and HCl in rats. Dig Dis Sci. 1981 Jun;26(6):538-44. doi: 10.1007/BF01308104. PMID: 6165534.

16: MUTTI F, CHIARI A. [On the choleretic activity of some derivatives of 1-phenyl-1-hydroxy-n-pentane and 1-phenyl-1-hydroxy-n-hexane]. Boll Chim Farm. 1961 Nov;100:846-50. Italian. PMID: 14477635.

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19: Ohki A, Otsuki M, Sakamoto C, Yuu H, Baba S. [Pancreatic exocrine function in rats treated with oral 1-phenyl-1-hydroxy-n-pentane (author's transl)]. Nihon Shokakibyo Gakkai Zasshi. 1982 Mar;79(3):845-50. Japanese. PMID: 7098123.

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