Pirifibrate

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 592620

CAS#: 21550-30-1

Description: Pirifibrate is used in the treatment of hyperlipoproteinemia.

Chemical Structure

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Pirifibrate
CAS# 21550-30-1
Instruction

Theoretical Analysis

MedKoo Cat#: 592620
Name: Pirifibrate
CAS#: 21550-30-1
Chemical Formula: C17H19Cl2NO4
Exact Mass: 371.07
Molecular Weight: 372.240
Elemental Analysis: C, 54.85; H, 5.15; Cl, 19.05; N, 3.76; O, 17.19

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Pirifibrate; Bratenol

IUPAC/Chemical Name: (6-(Hydroxymethyl)-2-pyridyl)methyl 2-(4-chlorophenoxy)-2-methylpropionate hydrochloride

InChi Key: XVHPKZBGSLSNOT-UHFFFAOYSA-N

InChi Code: InChI=1S/C17H18ClNO4.ClH/c1-17(2,23-15-8-6-12(18)7-9-15)16(21)22-11-14-5-3-4-13(10-20)19-14;/h3-9,20H,10-11H2,1-2H3;1H

SMILES Code: CC(C)(OC1=CC=C(Cl)C=C1)C(OCC2=NC(CO)=CC=C2)=O.[H]Cl

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 372.24 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Lopez Rodriguez J, Martorell J. Pirifibrate in the treatment of hyperlipoproteinemia: types IIa, IIb, and IV. Clin Ther. 1980;3(4):234-41. PubMed PMID: 7273061.

2: Bonora V, Calalabuig RJ, Caviola E, Soler J, Pueyo JM, Micaló T, Cano RP. Treatment of hyperlipoproteinemia, types II and IV, with pirifibrate: one hundred observations. Clin Ther. 1981;4(3):192-200. PubMed PMID: 7030489.

3: Domingo AJ, Gutiérrez JA, Menéndez JA, Micó L, Muñoz M, de Oya M. Pirifibrate in the treatment of hyperlipoproteinemias: a multicenter study. Clin Ther. 1980;3(3):219-26. PubMed PMID: 7459931.

4: de la Fuente R, Santos M. [Toxicological and pharmacological studies on a new drug: pirfibrate (EL-466) (author's transl)]. Arch Farmacol Toxicol. 1980 Dec;6(3):255-64. Spanish. PubMed PMID: 7305456.