Epibatidine 2HCl

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 563429

CAS#: 166374-43-2

Description: Epibatidine 2HCl is a potent nicotinic agonist.

Chemical Structure

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Epibatidine 2HCl
CAS# 166374-43-2
Instruction

Theoretical Analysis

MedKoo Cat#: 563429
Name: Epibatidine 2HCl
CAS#: 166374-43-2
Chemical Formula: C11H15Cl3N2
Exact Mass: 0.00
Molecular Weight: 281.600
Elemental Analysis: C, 46.92; H, 5.37; Cl, 37.77; N, 9.95

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Epibatidine Dihydrochloride; Epibatidine 2HCl; Epibatidine HCl;

IUPAC/Chemical Name: 2-(6-chloropyridin-3-yl)-7-azabicyclo[2.2.1]heptane dihydrochloride

InChi Key: DGNNWUINALNROG-UHFFFAOYSA-N

InChi Code: InChI=1S/C11H13ClN2.2ClH/c12-11-4-1-7(6-13-11)9-5-8-2-3-10(9)14-8;;/h1,4,6,8-10,14H,2-3,5H2;2*1H

SMILES Code: ClC1=CC=C(C2C(N3)CCC3C2)C=N1.[H]Cl.[H]Cl

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 281.60 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Quik M, Sum JD, Whiteaker P, McCallum SE, Marks MJ, Musachio J, McIntosh JM, Collins AC, Grady SR. Differential declines in striatal nicotinic receptor subtype function after nigrostriatal damage in mice. Mol Pharmacol. 2003 May;63(5):1169-79. PubMed PMID: 12695545.

2: Kulak JM, McIntosh JM, Quik M. Loss of nicotinic receptors in monkey striatum after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine treatment is due to a decline in alpha-conotoxin MII sites. Mol Pharmacol. 2002 Jan;61(1):230-8. PubMed PMID: 11752225.