PEG-9 Laurate

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 598451

CAS#: 106-08-1

Description: PEG-9 Laurate is a bioactive chemical.

Chemical Structure

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PEG-9 Laurate
CAS# 106-08-1
Instruction

Theoretical Analysis

MedKoo Cat#: 598451
Name: PEG-9 Laurate
CAS#: 106-08-1
Chemical Formula: C30H60O11
Exact Mass: 596.41
Molecular Weight: 596.790
Elemental Analysis: C, 60.38; H, 10.13; O, 29.49

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: PEG-9 Laurate; Lipal 4L; Lipal 4ML; NGML; NSC 1249; NSC-1249; NSC1249;

IUPAC/Chemical Name: 26-hydroxy-3,6,9,12,15,18,21,24-octaoxahexacosyl dodecanoate

InChi Key: FGGVRPFJBBRZFG-UHFFFAOYSA-N

InChi Code: InChI=1S/C30H60O11/c1-2-3-4-5-6-7-8-9-10-11-30(32)41-29-28-40-27-26-39-25-24-38-23-22-37-21-20-36-19-18-35-17-16-34-15-14-33-13-12-31/h31H,2-29H2,1H3

SMILES Code: CCCCCCCCCCCC(OCCOCCOCCOCCOCCOCCOCCOCCOCCO)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 596.79 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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8: He WS, Yin J, Xu HS, Qian QY, Jia CS, Ma HL, Feng B. Efficient synthesis and characterization of ergosterol laurate in a solvent-free system. J Agric Food Chem. 2014 Dec 3;62(48):11748-55. doi: 10.1021/jf504516q. Epub 2014 Nov 18. PubMed PMID: 25405492.

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10: Kragh-Hansen U, Pedersen AO, Galliano M, Minchiotti L, Brennan SO, Tárnoky AL, Franco MH, Salzano FM. High-affinity binding of laurate to naturally occurring mutants of human serum albumin and proalbumin. Biochem J. 1996 Dec 15;320 ( Pt 3):911-6. PubMed PMID: 9003380; PubMed Central PMCID: PMC1218015.

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12: Samartsev VN, Simonyan RA, Markova OV, Mokhova EN, Skulachev VP. Comparative study on uncoupling effects of laurate and lauryl sulfate on rat liver and skeletal muscle mitochondria. Biochim Biophys Acta. 2000 Jul 20;1459(1):179-90. PubMed PMID: 10924910.

13: Inami Y, Andoh T, Sasaki A, Kuraishi Y. Topical surfactant-induced pruritus: involvement of histamine released from epidermal keratinocytes. J Pharmacol Exp Ther. 2013 Feb;344(2):459-66. doi: 10.1124/jpet.112.200063. Epub 2012 Dec 5. PubMed PMID: 23220712.

14: Chang SW, Shaw JF, Shieh CH, Shieh CJ. Optimal formation of hexyl laurate by Lipozyme IM-77 in solvent-free system. J Agric Food Chem. 2006 Sep 20;54(19):7125-9. PubMed PMID: 16968072.

15: Knutzon DS, Hayes TR, Wyrick A, Xiong H, Maelor Davies H, Voelker TA. Lysophosphatidic acid acyltransferase from coconut endosperm mediates the insertion of laurate at the sn-2 position of triacylglycerols in lauric rapeseed oil and can increase total laurate levels . Plant Physiol. 1999 Jul;120(3):739-46. PubMed PMID: 10398708; PubMed Central PMCID: PMC59311.

16: Nilsson HM, Meany B, Ticey J, Sun CF, Wang Y, Cumings J. Ammonium Laurate Surfactant for Cleaner Deposition of Carbon Nanotubes. Langmuir. 2015 Jun 30;31(25):6948-55. doi: 10.1021/acs.langmuir.5b01175. Epub 2015 Jun 15. PubMed PMID: 26020583.

17: Kong X, Yuan H, Wu X, Zhang J, Zhou H, Wang M, Liu Y, Jin X. High-mobility-group box protein 1A box reduces development of sodium laurate-induced thromboangiitis obliterans in rats. J Vasc Surg. 2013 Jan;57(1):194-204. doi: 10.1016/j.jvs.2012.06.083. Epub 2012 Oct 13. PubMed PMID: 23069071.

18: Bani-Jaber A, Kobayashi A, Yamada K, Haj-Ali D, Uchimoto T, Iwao Y, Noguchi S, Itai S. A newly developed lubricant, chitosan laurate, in the manufacture of acetaminophen tablets. Int J Pharm. 2015 Apr 10;483(1-2):49-56. doi: 10.1016/j.ijpharm.2015.02.014. Epub 2015 Feb 7. PubMed PMID: 25667982.

19: Final report of the amended safety assessment of Glyceryl Laurate, Glyceryl Laurate SE, Glyceryl Laurate/Oleate, Glyceryl Adipate, Glyceryl Alginate, Glyceryl Arachidate, Glyceryl Arachidonate, Glyceryl Behenate, Glyceryl Caprate, Glyceryl Caprylate, Glyceryl Caprylate/Caprate, Glyceryl Citrate/Lactate/Linoleate/Oleate, Glyceryl Cocoate, Glyceryl Collagenate, Glyceryl Erucate, Glyceryl Hydrogenated Rosinate, Glyceryl Hydrogenated Soyate, Glyceryl Hydroxystearate, Glyceryl Isopalmitate, Glyceryl Isostearate, Glyceryl Isostearate/Myristate, Glyceryl Isostearates, Glyceryl Lanolate, Glyceryl Linoleate, Glyceryl Linolenate, Glyceryl Montanate, Glyceryl Myristate, Glyceryl Isotridecanoate/Stearate/Adipate, Glyceryl Oleate SE, Glyceryl Oleate/Elaidate, Glyceryl Palmitate, Glyceryl Palmitate/Stearate, Glyceryl Palmitoleate, Glyceryl Pentadecanoate, Glyceryl Polyacrylate, Glyceryl Rosinate, Glyceryl Sesquioleate, Glyceryl/Sorbitol Oleate/Hydroxystearate, Glyceryl Stearate/Acetate, Glyceryl Stearate/Maleate, Glyceryl Tallowate, Glyceryl Thiopropionate, and Glyceryl Undecylenate. Int J Toxicol. 2004;23 Suppl 2:55-94. Review. PubMed PMID: 15513825.

20: Messinger H, Bär A. Oral 4-week and 13-week toxicity studies of polyvinyl acetate vinyl laurate copolymer in rats. Regul Toxicol Pharmacol. 2014 Oct;70(1):1-6. doi: 10.1016/j.yrtph.2014.06.008. Epub 2014 Jun 14. PubMed PMID: 24932800.